SCHEMBL29924650

SCHEMBL29924650

NCc1ccc(C2=CN3c4ccccc4SC3N2CCCN2CCCCC2)c(F)c1

nearest known ligand 0.36

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ FPR2 P25090 2/20 0.36
▸ LTA4H P09960 1/20 0.33
▸ NPSR1 Q6W5P4 1/20 0.32
▸ KDM1A O60341 4/20 0.31
▸ DRD2 P14416 2/20 0.31
▸ SLC6A4 P31645 1/20 0.31
▸ SLC6A3 Q01959 1/20 0.31
▸ PRMT6 Q96LA8 1/20 0.31
▸ ALDH1A1 P00352 1/20 0.31
▸ HTT P42858 1/20 0.31
▸ CD274 Q9NZQ7 1/20 0.30
▸ MEN1 O00255 1/20 0.30
▸ GAA P10253 1/20 0.30
▸ KMT2A Q03164 1/20 0.30
▸ L3MBTL1 Q9Y468 1/20 0.30
▸ HRH3 Q9Y5N1 1/20 0.30
▸ SIGMAR1 Q99720 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29925063 0.90 CD274 (0.37) FPR2NPSR1KDM1ADRD2SLC6A4
SCHEMBL29924990 0.89 ADRA1D (0.33) FPR2KDM1ADRD2HRH3
SCHEMBL29924999 0.83 BCHE (0.30) SLC6A3ALDH1A1HRH3
SCHEMBL29925414 0.82 FPR2 (0.34) FPR2KDM1ASLC6A4SLC6A3L3MBTL1
SCHEMBL29924718 0.82 FPR2 (0.34) FPR2KDM1ASLC6A4SLC6A3L3MBTL1
SCHEMBL29925004 0.80 KCNH2 (0.44) DRD2SLC6A4SLC6A3ALDH1A1MEN1
SCHEMBL30085699 0.79 HRH3 (0.39) FPR2KDM1AALDH1A1MEN1KMT2A
SCHEMBL29924699 0.78 FPR2 (0.34) FPR2NPSR1KDM1ADRD2SLC6A4
SCHEMBL29924781 0.78 FPR2 (0.34) FPR2KDM1AHRH3
SCHEMBL30085708 0.76 HRH3 (0.37) FPR2NPSR1KDM1ADRD2SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4274569-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER Anima Biotech Inc. (US) 2023-11-15 — — EP disclosed
WO-2022150316-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC. (US) 2022-07-14 — — WO disclosed
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