Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLP1R | P43220 | 19/20 | 0.40 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.39 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29149813 | 1.00 | GLP1R (0.40) | GLP1RSRD5A2CYP2C8HTR2AKCNH2 | |
| SCHEMBL29149806 | 1.00 | GLP1R (0.40) | GLP1RSRD5A2CYP2C8HTR2AKCNH2 | |
| SCHEMBL30680670 | 0.92 | PKM (0.39) | — | |
| SCHEMBL30680774 | 0.92 | PKM (0.39) | — | |
| SCHEMBL29149793 | 0.92 | PKM (0.39) | — | |
| SCHEMBL29149786 | 0.92 | PKM (0.39) | — | |
| SCHEMBL22527875 | 0.83 | THRB (0.38) | — | |
| SCHEMBL22527873 | 0.83 | THRB (0.38) | — | |
| SCHEMBL29924969 | 0.81 | GLP1R (0.54) | GLP1RCYP2C8KCNH2 | |
| SCHEMBL29149716 | 0.81 | GLP1R (0.43) | GLP1RCYP2C8HTR2AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022228490-A1 | POLYCYCLIC DERIVATIVE MODULATOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海翰森生物医药科技有限公司 | 2022-11-03 | — | — | WO | disclosed |