Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.69 |
| ▸ | NPC1 | O15118 | 2/20 | 0.69 |
| ▸ | ATM | Q13315 | 1/20 | 0.69 |
| ▸ | HPGD | P15428 | 2/20 | 0.68 |
| ▸ | LMNA | P02545 | 5/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
| ▸ | TP53 | P04637 | 3/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | THRB | P10828 | 3/20 | 0.60 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.59 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29924997 | 0.95 | MAPT (0.62) | MAPTALDH1A1KDM4ENPC1ATM | |
| SCHEMBL29924760 | 0.91 | LMNA (0.61) | MAPTALDH1A1KDM4ENPC1ATM | |
| SCHEMBL29924901 | 0.89 | MAPT (0.59) | MAPTALDH1A1KDM4ENPC1ATM | |
| SCHEMBL29925371 | 0.89 | LMNA (0.56) | MAPTALDH1A1KDM4ENPC1ATM | |
| SCHEMBL29925218 | 0.88 | MAPT (0.72) | MAPTALDH1A1KDM4ENPC1ATM | |
| SCHEMBL30086015 | 0.88 | LMNA (0.54) | MAPTALDH1A1KDM4ENPC1ATM | |
| SCHEMBL24619541 | 0.87 | LMNA (0.66) | MAPTALDH1A1KDM4ENPC1ATM | |
| SCHEMBL29924792 | 0.86 | MAPT (0.76) | MAPTALDH1A1KDM4ENPC1ATM | |
| SCHEMBL24619493 | 0.86 | LMNA (0.79) | MAPTALDH1A1KDM4ENPC1ATM | |
| SCHEMBL29925104 | 0.85 | LMNA (0.63) | MAPTALDH1A1KDM4ENPC1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4274569-A1 | C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER | Anima Biotech Inc. (US) | 2023-11-15 | — | — | EP | disclosed |
| WO-2022150316-A1 | C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER | ANIMA BIOTECH INC. (US) | 2022-07-14 | — | — | WO | disclosed |