Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | THRB | P10828 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 4/20 | 0.52 |
| ▸ | ATM | Q13315 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | FLT3 | P36888 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29924693 | 0.89 | MAPT (0.69) | MAPTTHRBRAB9ASMN1; SMN2RXFP1 | |
| SCHEMBL24106013 | 0.89 | MAPT (0.69) | MAPTTHRBRAB9ASMN1; SMN2RXFP1 | |
| SCHEMBL29924811 | 0.88 | MAPT (0.57) | MAPTTHRBRAB9ASMN1; SMN2RXFP1 | |
| SCHEMBL24619383 | 0.86 | RAB9A (0.58) | MAPTTHRBRAB9ASMN1; SMN2RXFP1 | |
| Formic Acid SCHEMBL29924662 | 0.84 | MAPT (0.53) | MAPTTHRBRAB9ASMN1; SMN2RXFP1 | |
| SCHEMBL29925326 | 0.84 | MAPT (0.56) | MAPTTHRBRAB9ASMN1; SMN2RXFP1 | |
| SCHEMBL30537848 | 0.84 | MAPT (0.71) | MAPTTHRBRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL29925028 | 0.84 | MAPT (0.71) | MAPTTHRBRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL29925216 | 0.83 | THRB (0.72) | MAPTTHRBRAB9ASMN1; SMN2RXFP1 | |
| SCHEMBL7763808 | 0.81 | MAPT (0.53) | MAPTTHRBRAB9ASMN1; SMN2RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4274569-A1 | C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER | Anima Biotech Inc. (US) | 2023-11-15 | — | — | EP | disclosed |
| CN-116635028-A | Modulators of c-MYC mRNA translation and their use in the treatment of cancer | 艾尼莫生物科技公司 | 2023-08-22 | — | — | CN | disclosed |
| WO-2022150316-A1 | C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER | ANIMA BIOTECH INC. (US) | 2022-07-14 | — | — | WO | disclosed |