Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.53 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 2/20 | 0.46 |
| ▸ | FLT3 | P36888 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HK1 | P19367 | 1/20 | 0.42 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9569337 | 0.86 | MAPT (0.52) | MAPTRAB9ATP53SMN1; SMN2ADORA2A | |
| SCHEMBL84416 | 0.85 | RAB9A (0.64) | MAPTRAB9ATP53SMN1; SMN2LMNA | |
| SCHEMBL20893101 | 0.83 | TP53 (0.67) | MAPTRAB9ATP53SMN1; SMN2LMNA | |
| SCHEMBL11013680 | 0.83 | THRB (0.57) | MAPTRAB9ATP53SMN1; SMN2ADORA2A | |
| SCHEMBL9837374 | 0.83 | RAB9A (0.53) | MAPTRAB9ATP53SMN1; SMN2ADORA2A | |
| SCHEMBL9569354 | 0.83 | MAPT (0.56) | MAPTRAB9ATP53SMN1; SMN2LMNA | |
| SCHEMBL11010264 | 0.83 | MAPT (0.53) | MAPTRAB9ATP53SMN1; SMN2ADORA2A | |
| SCHEMBL29924932 | 0.81 | MAPT (0.58) | MAPTRAB9ATP53SMN1; SMN2LMNA | |
| SCHEMBL11011253 | 0.81 | MAPT (0.51) | MAPTRAB9ATP53SMN1; SMN2LMNA | |
| Hydrochloric Acid SCHEMBL11011106 | 0.81 | MAPT (0.51) | MAPTRAB9ATP53SMN1; SMN2ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2001048786-A | TRICYCLIC HETEROARYL DERIVATIVE | YAMANOUCHI PHARMACEUT CO LTD | 2001-02-20 | — | — | JP | disclosed |