Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 3/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | ACSS2 | Q9NR19 | 2/20 | 0.41 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CCNC | P24863 | 1/20 | 0.40 |
| ▸ | CDK8 | P49336 | 1/20 | 0.40 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.40 |
| ▸ | IP6K3 | Q96PC2 | 1/20 | 0.40 |
| ▸ | IP6K2 | Q9UHH9 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24619371 | 1.00 | PLK1 (0.45) | PLK1THRBHDAC6HDAC1HDAC8 | |
| SCHEMBL20017813 | 0.85 | PLK1 (0.46) | PLK1THRBHDAC6HDAC1HDAC8 | |
| SCHEMBL4129101 | 0.80 | CA1 (0.47) | SMN1; SMN2HPGDHTTTDP1GAA | |
| SCHEMBL4096586 | 0.79 | LMNA (0.49) | TSHRHTTTDP1GAA | |
| SCHEMBL531941 | 0.78 | CES2 (0.59) | THRBHDAC6HDAC1HDAC8HDAC2 | |
| SCHEMBL30147734 | 0.78 | CES2 (0.59) | THRBHDAC6HDAC1HDAC8HDAC2 | |
| SCHEMBL30147494 | 0.75 | HDAC6 (0.73) | PLK1THRBHDAC6HDAC1HDAC8 | |
| SCHEMBL8515075 | 0.75 | ESRRG (0.50) | PLK1THRBHDAC6HDAC1HDAC8 | |
| SCHEMBL29306646 | 0.75 | GAA (0.58) | PLK1THRBHDAC6HDAC1HDAC8 | |
| SCHEMBL1441177 | 0.75 | HDAC6 (0.73) | PLK1THRBHDAC6HDAC1HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4274569-A1 | C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER | Anima Biotech Inc. (US) | 2023-11-15 | — | — | EP | disclosed |
| WO-2022150316-A1 | C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER | ANIMA BIOTECH INC. (US) | 2022-07-14 | — | — | WO | disclosed |