Jaceosidine

Jaceosidine

SCHEMBL29926544

COc1cc(-c2cc(=O)c3c(O)c(OC)c(O)cc3o2)ccc1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B2 P37059 1/20 1.00
TAS2R31 P59538 1/20 1.00
HDAC6 Q9UBN7 1/20 0.86
MEN1 O00255 5/20 0.82
POLB P06746 5/20 0.82
MAPT P10636 5/20 0.82
KMT2A Q03164 5/20 0.82
NPC1 O15118 3/20 0.82
GFER P55789 2/20 0.82
KDM4E B2RXH2 2/20 0.82
GAA P10253 2/20 0.82
RECQL P46063 2/20 0.82
AMY1A P0DUB6 1/20 0.82
THRB P10828 1/20 0.82
APEX1 P27695 1/20 0.82
BLM P54132 1/20 0.82
CASP6 P55212 1/20 0.82
FLT3 P36888 4/20 0.76
RAB9A P51151 2/20 0.76
GABRP O00591 1/20 0.76

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Jaceosidine SCHEMBL3960077 1.00 HSD17B2 (1.00) HSD17B2TAS2R31HDAC6MEN1POLB
Eupatilin SCHEMBL29926197 0.93 HDAC6 (1.00) HSD17B2TAS2R31HDAC6MEN1POLB
Eupatilin SCHEMBL29568655 0.93 HDAC6 (1.00) HSD17B2TAS2R31HDAC6MEN1POLB
Cirsileneol SCHEMBL2045672 0.93 HSD17B2 (0.86) HSD17B2TAS2R31HDAC6MEN1POLB
Eupatilin SCHEMBL1033509 0.93 HDAC6 (1.00) HSD17B2TAS2R31HDAC6MEN1POLB
Cirsileneol SCHEMBL29435128 0.93 HSD17B2 (0.86) HSD17B2TAS2R31HDAC6MEN1POLB
SCHEMBL30799172 0.90 FLT3 (0.86) HSD17B2TAS2R31HDAC6MEN1POLB
SCHEMBL8069022 0.90 FLT3 (0.86) HSD17B2TAS2R31HDAC6MEN1POLB
SCHEMBL6239788 0.90 HSD17B2 (0.82) HSD17B2TAS2R31HDAC6MEN1POLB
SCHEMBL29906158 0.90 HSD17B2 (0.82) HSD17B2TAS2R31HDAC6MEN1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023064318-A1 BIPHASIC COMPOSITIONS COMPRISING ONE OR BOTH OF CARBONATE AND PHOSPHATE Natural Extraction Systems, LLC (US) 2023-04-20 WO claimed
CN-115315195-A Hydroxy-and methoxy-substituted flavonoids and their use 弗门尼舍有限公司 2022-11-08 CN claimed
WO-2022182527-A1 COMPOSITIONS AND METHODS RELATED TO PHARMACEUTICAL EXCIPIENTS Natural Extraction Systems, LLC (US) 2022-09-01 WO claimed
CN-115315195-B Hydroxy-and methoxy-substituted flavonoids and use thereof 弗门尼舍有限公司 2024-07-02 CN disclosed
CN-118108692-A Method for rapidly extracting and separating eupatilin and brown cyanidin from north mugwort 安阳工学院 2024-05-31 CN disclosed
EP-4258900-A1 HYDROXY- AND METHOXY-SUBSTITUTED FLAVONOIDS AND THEIR USE Firmenich SA (CH) 2023-10-18 EP disclosed
WO-2023064318-A1 BIPHASIC COMPOSITIONS COMPRISING ONE OR BOTH OF CARBONATE AND PHOSPHATE Natural Extraction Systems, LLC (US) 2023-04-20 WO disclosed
CN-115315195-A Hydroxy-and methoxy-substituted flavonoids and their use 弗门尼舍有限公司 2022-11-08 CN disclosed
WO-2022189156-A1 HYDROXY- AND METHOXY-SUBSTITUTED FLAVONOIDS AND THEIR USE FIRMENICH SA (CH) 2022-09-15 WO disclosed