Jaceosidine

Jaceosidine

SCHEMBL3960077

COc1cc(-c2cc(=O)c3c(O)c(OC)c(O)cc3o2)ccc1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B2 P37059 1/20 1.00
TAS2R31 P59538 1/20 1.00
HDAC6 Q9UBN7 1/20 0.86
MEN1 O00255 5/20 0.82
POLB P06746 5/20 0.82
MAPT P10636 5/20 0.82
KMT2A Q03164 5/20 0.82
NPC1 O15118 3/20 0.82
GFER P55789 2/20 0.82
KDM4E B2RXH2 2/20 0.82
GAA P10253 2/20 0.82
RECQL P46063 2/20 0.82
AMY1A P0DUB6 1/20 0.82
THRB P10828 1/20 0.82
APEX1 P27695 1/20 0.82
BLM P54132 1/20 0.82
CASP6 P55212 1/20 0.82
FLT3 P36888 4/20 0.76
RAB9A P51151 2/20 0.76
GABRP O00591 1/20 0.76

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Jaceosidine SCHEMBL29926544 1.00 HSD17B2 (1.00) HSD17B2TAS2R31HDAC6MEN1POLB
Eupatilin SCHEMBL29926197 0.93 HDAC6 (1.00) HSD17B2TAS2R31HDAC6MEN1POLB
Eupatilin SCHEMBL29568655 0.93 HDAC6 (1.00) HSD17B2TAS2R31HDAC6MEN1POLB
Cirsileneol SCHEMBL2045672 0.93 HSD17B2 (0.86) HSD17B2TAS2R31HDAC6MEN1POLB
Eupatilin SCHEMBL1033509 0.93 HDAC6 (1.00) HSD17B2TAS2R31HDAC6MEN1POLB
Cirsileneol SCHEMBL29435128 0.93 HSD17B2 (0.86) HSD17B2TAS2R31HDAC6MEN1POLB
SCHEMBL30799172 0.90 FLT3 (0.86) HSD17B2TAS2R31HDAC6MEN1POLB
SCHEMBL8069022 0.90 FLT3 (0.86) HSD17B2TAS2R31HDAC6MEN1POLB
SCHEMBL6239788 0.90 HSD17B2 (0.82) HSD17B2TAS2R31HDAC6MEN1POLB
SCHEMBL29906158 0.90 HSD17B2 (0.82) HSD17B2TAS2R31HDAC6MEN1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 253 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4698662-A2 REGULATABLE CONTROLLED EXPRESSION OF A TRANSGENE IN PRIMATES AskBio Inc. (US) 2026-02-25 EP claimed
US-20250127199-A1 COMPOSITION COMPRISING A NUTRIENT AND A TASTE MODULATOR FIRMENICH SA (CH) 2025-04-24 US claimed
WO-2024220449-A9 REGULATABLE CONTROLLED EXPRESSION OF A TRANSGENE IN PRIMATES AskBio Inc. (US) 2025-04-03 WO claimed
CN-116459287-B Application of lindley eupatorium herb ethanol extract and flavone part thereof in preparation of medicines for preventing or treating ulcerative colitis 苏州大学 2025-03-21 CN claimed
US-20250011393-A1 FLAVONOID-COLLAGEN CROSSLINKED ANTIOXIDANT HYDROGEL NORTH CAROLINA STATE UNIVERSITY 2025-01-09 US claimed
WO-2024220449-A2 REGULATABLE CONTROLLED EXPRESSION OF A TRANSGENE IN PRIMATES ASKLEPIOS BIOPHARMACEUTICAL, INC. (US) 2024-10-24 WO claimed
US-20240315965-A1 COMPOSITIONS AND METHODS RELATED TO PHARMACEUTICAL EXCIPIENTS Natural Extraction Systems, LLC (US) 2024-09-26 US claimed
EP-4384027-A1 COMPOSITION COMPRISING A NUTRIENT AND A TASTE MODULATOR Firmenich SA (CH) 2024-06-19 EP claimed
CN-118108692-A Method for rapidly extracting and separating eupatilin and brown cyanidin from north mugwort 安阳工学院 2024-05-31 CN claimed
US-20240099344-A1 HYDROXY- AND METHOXY-SUBSTITUTED FLAVONOIDS AND THEIR USE FIRMENICH SA (CH) 2024-03-28 US claimed
WO-2021158573-A1 METHODS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES Natural Extraction Systems, LLC (US) 2021-08-12 WO claimed
WO-2021158575-A1 COMPOSITIONS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES Natural Extraction Systems, LLC (US) 2021-08-12 WO claimed
CN-107854507-B Method for extracting flavonoid component from folium artemisiae argyi 山东省中医药研究院 2021-01-22 CN claimed
CN-108113985-B Application of eupatorium lindleyanum flavone part in preparation of anti-hepatitis B virus medicines 苏州大学 2020-07-21 CN claimed
CN-110824047-A Method for judging fluff beating proportion of folium artemisiae argyi 天津中医药大学 2020-02-21 CN claimed
CN-107854692-B Pharmaceutical composition for treating lipopexia and application thereof 延边大学 2019-12-31 CN claimed
EP-3421035-A1 NOVEL USE OF CHROMONE DERIVATIVE AS PHARMACEUTICAL COMPOSITION FOR PREVENTING AND TREATING FIBROSIS BY USING EPITHELIAL-MESENCHYMAL TRANSITION INHIBITORY ACTIVITY THEREOF Osteoneurogen Inc. (KR) 2019-01-02 EP claimed
US-20170239211-A1 USE OF CHROMONE DERIVATIVE AS PHARMACEUTICAL COMPOSITION FOR PREVENTION AND TREATMENT OF FIBROSIS USING EMT INHIBITORY ACTIVITY OSTEONEUROGEN INC. (KR) 2017-08-24 US claimed
CN-106306395-A Sweet potato residue feed and preparation method thereof 自然味(重庆)农业科技股份有限公司 2017-01-11 CN claimed
WO-2006004358-A1 DICOUMAROL-REMOVED EXTRACT OF ARTEMISIA, PREPARATION AND PHARMACEUTICAL COMPOSITIONS THEREOF DONG-A PHARM. CO., LTD. (KR) 2006-01-12 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170239211-A1 USE OF CHROMONE DERIVATIVE AS PHARMACEUTICAL COMPOSITION FOR PREVENTION AND TREATMENT OF FIBROSIS USING EMT INHIBITORY ACTIVITY CDH1, SMAD3, SMAD2 HSD17B2 220/4885TAS2R31 4176/4885HDAC6 1189/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.