SCHEMBL2992706

SCHEMBL2992706

Cc1c(Cc2c(C(C)(C)C)cc(O)cc2C(C)(C)C)c(C)c(C2(C)C(C(C)(C)C)=CC(O)C=C2C(C)(C)C)c(C)c1Cc1c(C(C)(C)C)cc(O)cc1C(C)(C)C

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.34
CYP2C9 P11712 1/20 0.34
CYP2C19 P33261 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
HIF1A Q16665 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL131955 0.78 CYP2C9 (0.50) TP53CYP2C9CYP2C19SMN1; SMN2HIF1A
SCHEMBL68860 0.71 CYP2C9 (0.48) TP53CYP2C9CYP2C19SMN1; SMN2HIF1A
SCHEMBL10891430 0.65 CYP2C9 (0.46) TP53CYP2C9CYP2C19SMN1; SMN2HIF1A
SCHEMBL105825 0.60 ALDH1A1 (0.52) TP53CYP2C9CYP2C19SMN1; SMN2HIF1A
SCHEMBL9007185 0.59 LMNA (0.48) CYP2C9SMN1; SMN2
SCHEMBL12620451 0.59 ALDH1A1 (0.52) TP53CYP2C9CYP2C19SMN1; SMN2HIF1A
SCHEMBL8518795 0.59 CYP2C9 (0.40) TP53CYP2C9CYP2C19SMN1; SMN2HIF1A
SCHEMBL27877808 0.59 ALDH1A1 (0.46) TP53CYP2C9CYP2C19SMN1; SMN2HIF1A
SCHEMBL2679857 0.59 ALDH1A1 (0.46) TP53CYP2C9CYP2C19SMN1; SMN2HIF1A
SCHEMBL31332412 0.58 HSPA5 (0.50) TP53CYP2C9CYP2C19SMN1; SMN2HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8217130-B2 Curable composition and method for producing the same CEMEDINE CO., LTD. (JP) 2012-07-10 US disclosed
EP-2093252-B1 Curing composition and method for producing curing composition CEMEDINE CO LTD (JP) 2012-05-16 EP disclosed
US-20100267898-A1 CURABLE COMPOSITION AND METHOD FOR PRODUCING THE SAME CEMEDINE CO., LTD. 2010-10-21 US disclosed
EP-1650257-B1 CURING COMPOSITION AND METHOD FOR PRODUCING CURING COMPOSITION CEMEDINE CO LTD (JP) 2010-09-08 EP disclosed
US-7781559-B2 Curable composition and method for producing the same CEMEDINE CO., LTD. (JP) 2010-08-24 US disclosed
EP-2093252-A1 Curing composition and method for producing curing composition CEMEDINE CO., LTD. (JP) 2009-08-26 EP disclosed
US-20060293456-A1 Curable composition and method for producing the same CEMEDINE CO., LTD. (JP) 2006-12-28 US disclosed
EP-1650257-A1 CURING COMPOSITION AND METHOD FOR PRODUCING CURING COMPOSITION CEMEDINE CO., LTD. (JP) 2006-04-26 EP disclosed