Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTO1 | P78417 | 3/20 | 0.54 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.41 |
| ▸ | BCL2A1 | Q16548 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | AKT1 | P31749 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL169432 | 0.87 | ALDH1A1 (0.46) | GSTO1PSMB5ALDH1A1GLATSHR | |
| SCHEMBL17666061 | 0.84 | PSMB5 (0.47) | GSTO1PSMB5BCL2A1CYP2C19 | |
| SCHEMBL20314798 | 0.82 | GSTO1 (0.58) | GSTO1PSMB5ALDH1A1GLATSHR | |
| SCHEMBL20314802 | 0.82 | PSMB5 (0.50) | GSTO1PSMB5ALDH1A1BCL2A1 | |
| SCHEMBL25434439 | 0.81 | BCL2A1 (0.44) | GSTO1PSMB5ALDH1A1GLATSHR | |
| SCHEMBL194846 | 0.81 | ALDH1A1 (0.63) | ALDH1A1GLATSHRTRPM8MEN1 | |
| SCHEMBL19456786 | 0.81 | NPC1 (0.51) | GSTO1PSMB5ALDH1A1GLATSHR | |
| SCHEMBL4202416 | 0.81 | ALDH1A1 (0.44) | GSTO1PSMB5ALDH1A1GLATSHR | |
| SCHEMBL17666060 | 0.80 | BCL2A1 (0.44) | GSTO1PSMB5BCL2A1 | |
| SCHEMBL27847921 | 0.80 | TRPM8 (0.64) | GSTO1ALDH1A1GLATRPM8BCL2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190119415-A1 | GRAFT COPOLYMER FOR CATION-EXCHANGE CHROMATOGRAPHY | MERCK PATENT GMBH (DE) | 2019-04-25 | — | — | US | claimed |
| EP-2152405-B2 | GRAFT COPOLYMER FOR CATION-EXCHANGE CHROMATOGRAPHY | MERCK PATENT GMBH (DE) | 2017-04-05 | — | — | EP | claimed |
| US-20140183136-A1 | GRAFT COPOLYMER FOR CATION-EXCHANGE CHROMATOGRAPHY | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2014-07-03 | — | — | US | claimed |
| EP-2152405-B1 | GRAFT COPOLYMER FOR CATION-EXCHANGE CHROMATOGRAPHY | MERCK PATENT GMBH (DE) | 2012-10-17 | — | — | EP | claimed |
| US-20100181254-A1 | GRAFT COPOLYMER FOR CATION- EXCHANGE CHROMATOGRAPHY | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2010-07-22 | — | — | US | claimed |
| EP-2152405-A1 | GRAFT COPOLYMER FOR CATION-EXCHANGE CHROMATOGRAPHY | Merck Patent GmbH (DE) | 2010-02-17 | — | — | EP | claimed |
| WO-2008145270-A1 | GRAFT COPOLYMER FOR CATION-EXCHANGE CHROMATOGRAPHY | MERCK PATENT GMBH (DE) | 2008-12-04 | — | — | WO | claimed |
| US-10669289-B2 | Boronic acid derivatives | MERCK PATENT GMBH (DE) | 2020-06-02 | — | — | US | disclosed |
| EP-3201206-B1 | BORONIC ACID DERIVATIVES | MERCK PATENT GMBH (DE) | 2019-09-18 | — | — | EP | disclosed |
| US-20190119415-A1 | GRAFT COPOLYMER FOR CATION-EXCHANGE CHROMATOGRAPHY | MERCK PATENT GMBH (DE) | 2019-04-25 | — | — | US | disclosed |
| US-20180179232-A1 | BORONIC ACID DERIVATIVES | MERCK PATENT GMBH (DE) | 2018-06-28 | — | — | US | disclosed |
| US-20180179232-A1 | BORONIC ACID DERIVATIVES | MERCK PATENT GMBH (DE) | 2018-06-28 | — | — | US | disclosed |
| EP-2152405-B2 | GRAFT COPOLYMER FOR CATION-EXCHANGE CHROMATOGRAPHY | MERCK PATENT GMBH (DE) | 2017-04-05 | — | — | EP | disclosed |
| EP-1734057-B1 | Temperature, irradiation or polymerization indicators | HERAEUS KULZER GMBH (DE) | 2009-03-25 | — | — | EP | disclosed |
| WO-2008145270-A1 | GRAFT COPOLYMER FOR CATION-EXCHANGE CHROMATOGRAPHY | MERCK PATENT GMBH (DE) | 2008-12-04 | — | — | WO | disclosed |
| US-20070218404-A1 | Infrared-sensitive lithographic printing plate | FUJIFILM CORPORATION (JP) | 2007-09-20 | — | — | US | disclosed |
| US-20070218404-A1 | Infrared-sensitive lithographic printing plate | FUJIFILM CORPORATION (JP) | 2007-09-20 | — | — | US | disclosed |
| EP-1734057-A2 | Temperature, irradiation or polymerization indicators | Heraeus Kulzer GmbH (DE) | 2006-12-20 | — | — | EP | disclosed |
| US-20060280649-A1 | Temperature/irradiation/polymerization indicators | HERAEUS KULZER GMBH (DE) | 2006-12-14 | — | — | US | disclosed |
| US-4308014-A | AN UNSATURATED ESTER OR AMIDE, A TITANIUM ALKOXIDE OR A TRIALKOXY SILANE, A FREE RADICAL CATALYST AND AN ACTIVATOR; DENTISTRY | KANEBO LTD. (JP) | 1981-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10669289-B2 | Boronic acid derivatives | BCL9, BCL9L, BCL6 | GSTO1 2482/4885PSMB5 105/4885ALDH1A1 1217/4885 |
| US-20180179232-A1 | BORONIC ACID DERIVATIVES | BCL9, BCL9L, BCL6 | GSTO1 2482/4885PSMB5 105/4885ALDH1A1 1217/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.