SCHEMBL2992719

SCHEMBL2992719

CC1(C2CCC3CCCC32)CCC2CCCC21

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 2/20 0.36
ESR1 P03372 1/20 0.33
AR P10275 1/20 0.33
ESR2 Q92731 1/20 0.33
GABRP O00591 2/20 0.31
GABRD O14764 2/20 0.31
GABRA1 P14867 2/20 0.31
GABRB1 P18505 2/20 0.31
GABRG2 P18507 2/20 0.31
GABRB3 P28472 2/20 0.31
GABRA5 P31644 2/20 0.31
GABRA3 P34903 2/20 0.31
GABRA2 P47869 2/20 0.31
GABRB2 P47870 2/20 0.31
GABRA4 P48169 2/20 0.31
GABRE P78334 2/20 0.31
GABRA6 Q16445 2/20 0.31
GABRG1 Q8N1C3 2/20 0.31
GABRG3 Q99928 2/20 0.31
GABRQ Q9UN88 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2996486 0.79 CYP19A1 (0.33) CYP19A1
SCHEMBL2995587 0.77 CYP19A1 (0.37) CYP19A1
SCHEMBL3003235 0.77 CYP19A1 (0.31) CYP19A1
SCHEMBL17735537 0.73 GABRP (0.35) CYP19A1ESR1ARESR2GABRP
SCHEMBL3000617 0.72 HSD17B10 (0.37) SHBGCDK5CDK5R1NR1I3
SCHEMBL22844974 0.70 UGT2B7 (0.33) UGT2B7
SCHEMBL31028959 0.69 UGT2B7 (0.30) UGT2B7
SCHEMBL6756605 0.68 CDK5 (0.35) CYP19A1SHBGCDK5CDK5R1NR1I3
SCHEMBL3003200 0.68
SCHEMBL2991580 0.68 CDK5 (0.33) SHBGCDK5CDK5R1NR1I3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5283384-A Low viscosity IDEMITSU KOSAN CO., LTD. (JP) 1994-02-01 US claimed
EP-2009304-B1 TORQUE LIMITER JTEKT CORP (JP) 2014-10-01 EP disclosed
EP-2003353-B1 TORQUE LIMITER JTEKT CORP (JP) 2014-06-04 EP disclosed
US-8230986-B2 Torque limiter JTEKT CORPORATION (JP) 2012-07-31 US disclosed
US-8220609-B2 Torque limiter JTEKT CORPORATION (JP) 2012-07-17 US disclosed
US-20100184519-A1 TORQUE LIMITER JTEKT CORPORATION (JP) 2010-07-22 US disclosed
US-20090173591-A1 TORQUE LIMITER JTEKT CORPORATION (JP) 2009-07-09 US disclosed
EP-2009304-A1 TORQUE LIMITER JTEKT Corporation (JP) 2008-12-31 EP disclosed
EP-2003353-A1 TORQUE LIMITER JTEKT Corporation (JP) 2008-12-17 EP disclosed
EP-0508292-B1 Traction drive fluid, process for producing the same and bicyclo octane compound IDEMITSU KOSAN CO (JP) 1996-08-28 EP disclosed
US-5283384-A Low viscosity IDEMITSU KOSAN CO., LTD. (JP) 1994-02-01 US disclosed
EP-0508292-A1 Traction drive fluid, process for producing the same and bicyclo octane compound IDEMITSU KOSAN COMPANY LIMITED (JP) 1992-10-14 EP disclosed