Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 4/20 | 0.35 |
| ▸ | GABRD | O14764 | 4/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 4/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 4/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 4/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 4/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.35 |
| ▸ | GABRA4 | P48169 | 4/20 | 0.35 |
| ▸ | GABRE | P78334 | 4/20 | 0.35 |
| ▸ | GABRA6 | Q16445 | 4/20 | 0.35 |
| ▸ | GABRG1 | Q8N1C3 | 4/20 | 0.35 |
| ▸ | GABRG3 | Q99928 | 4/20 | 0.35 |
| ▸ | GABRQ | Q9UN88 | 4/20 | 0.35 |
| ▸ | SHBG | P04278 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.32 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.32 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4834980 | 0.76 | GABRD (0.42) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL14883711 | 0.74 | CDK5 (0.59) | CYP19A1CDK5CDK5R1KMT2AESR1 | |
| SCHEMBL2992719 | 0.73 | CYP19A1 (0.36) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL12178067 | 0.70 | SHBG (0.62) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL16189884 | 0.70 | SHBG (0.62) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL23569462 | 0.70 | GABRA1 (0.42) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL4833944 | 0.70 | GABRD (0.42) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL15164711 | 0.70 | SHBG (0.62) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL12178022 | 0.70 | SHBG (0.62) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL19114020 | 0.70 | LMNA (0.62) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160129017-A1 | SHIP INHIBITION TO COMBAT OBESITY | The Research Foundation for the State University New York (US) | 2016-05-12 | — | — | US | disclosed |
| US-20160129017-A1 | SHIP INHIBITION TO COMBAT OBESITY | The Research Foundation for the State University New York (US) | 2016-05-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160129017-A1 | SHIP INHIBITION TO COMBAT OBESITY | PPM1G, PPM1B, PPM1F | GABRP 3019/4885GABRD 3705/4885GABRA1 3830/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.