SCHEMBL2991580

SCHEMBL2991580

CC1(C2CC3CCC(C3)C2)CCC2CCCC21

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CDK5 Q00535 1/20 0.33
CDK5R1 Q15078 1/20 0.33
NR1I3 Q14994 1/20 0.33
HSD17B10 Q99714 1/20 0.31
SHBG P04278 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3000617 0.86 HSD17B10 (0.37) CDK5CDK5R1NR1I3HSD17B10SHBG
SCHEMBL2996486 0.78 CYP19A1 (0.33)
SCHEMBL2999913 0.70 LMNA (0.33) CDK5CDK5R1NR1I3HSD17B10SHBG
SCHEMBL11014352 0.68 CYP19A1 (0.42) HSD17B10
SCHEMBL2995208 0.68 CYP19A1 (0.39) CDK5CDK5R1NR1I3HSD17B10
SCHEMBL2997217 0.68 LMNA (0.39) HSD17B10SHBG
SCHEMBL2992719 0.68 CYP19A1 (0.36) CDK5CDK5R1NR1I3SHBG
SCHEMBL19253230 0.68 NR1I3 (0.57) NR1I3HSD17B10SHBG
SCHEMBL3003235 0.68 CYP19A1 (0.31)
SCHEMBL2995587 0.68 CYP19A1 (0.37)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5283384-A Low viscosity IDEMITSU KOSAN CO., LTD. (JP) 1994-02-01 US claimed
EP-2009304-B1 TORQUE LIMITER JTEKT CORP (JP) 2014-10-01 EP disclosed
EP-2003353-B1 TORQUE LIMITER JTEKT CORP (JP) 2014-06-04 EP disclosed
US-8230986-B2 Torque limiter JTEKT CORPORATION (JP) 2012-07-31 US disclosed
US-8220609-B2 Torque limiter JTEKT CORPORATION (JP) 2012-07-17 US disclosed
US-20100184519-A1 TORQUE LIMITER JTEKT CORPORATION (JP) 2010-07-22 US disclosed
US-20090173591-A1 TORQUE LIMITER JTEKT CORPORATION (JP) 2009-07-09 US disclosed
EP-2009304-A1 TORQUE LIMITER JTEKT Corporation (JP) 2008-12-31 EP disclosed
EP-2003353-A1 TORQUE LIMITER JTEKT Corporation (JP) 2008-12-17 EP disclosed
EP-0508292-B1 Traction drive fluid, process for producing the same and bicyclo octane compound IDEMITSU KOSAN CO (JP) 1996-08-28 EP disclosed
US-5283384-A Low viscosity IDEMITSU KOSAN CO., LTD. (JP) 1994-02-01 US disclosed
EP-0508292-A1 Traction drive fluid, process for producing the same and bicyclo octane compound IDEMITSU KOSAN COMPANY LIMITED (JP) 1992-10-14 EP disclosed