Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 5/20 | 0.33 |
| ▸ | GABRP | O00591 | 1/20 | 0.33 |
| ▸ | GABRD | O14764 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.33 |
| ▸ | GABRE | P78334 | 1/20 | 0.33 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.33 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11940150 | 0.86 | TDP1 (0.38) | TDP1CHRM4KDM4EMAPTATM | |
| SCHEMBL21887822 | 0.83 | TDP1 (0.66) | TDP1HCAR2ALDH1A1HPGDTSHR | |
| SCHEMBL29928384 | 0.81 | TDP1 (0.69) | TDP1HCAR2ALDH1A1HPGDTSHR | |
| SCHEMBL1424187 | 0.81 | TDP1 (0.69) | TDP1HCAR2ALDH1A1HPGDTSHR | |
| SCHEMBL1424813 | 0.81 | NPSR1 (0.42) | TDP1ALDH1A1HPGDCHRM4KMT2A | |
| SCHEMBL19187069 | 0.80 | TDP1 (0.56) | TDP1HCAR2KDM4E | |
| SCHEMBL1424210 | 0.79 | TDP1 (0.51) | TDP1HCAR2GABRPGABRDGABRA1 | |
| SCHEMBL21806451 | 0.79 | TDP1 (0.55) | TDP1HCAR2KDM4E | |
| SCHEMBL30151452 | 0.79 | TDP1 (0.55) | TDP1HCAR2KDM4E | |
| SCHEMBL16776875 | 0.78 | TDP1 (0.50) | TDP1HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170042152-A1 | SAFENED HERBICIDAL COMPOSITIONS COMPRISING PYRIDINE CARBOXYLIC ACIDS | DOW AGROSCIENCES LLC | 2017-02-16 | — | — | US | disclosed |
| US-20170042151-A1 | SAFENED HERBICIDAL COMPOSITIONS COMPRISING PYRIDINE CARBOXYLIC ACIDS | DOW AGROSCIENCES LLC | 2017-02-16 | — | — | US | disclosed |
| EP-1608624-B1 | 6-ALKYL OR ALKENYL-4-AMINOPICOLINATES AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2011-03-23 | — | — | EP | disclosed |
| US-7432227-B2 | 6-alkyl or alkenyl-4-aminopicolinates and their use as herbicides | DOW AGROSCIENCES LLC (US) | 2008-10-07 | — | — | US | disclosed |
| EP-1608624-A2 | 6-ALKYL OR ALKENYL-4-AMINOPICOLINATES AND THEIR USE AS HERBICIDES | Dow AgroSciences LLC (US) | 2005-12-28 | — | — | EP | disclosed |
| WO-2004089906-A2 | 6-ALKYL OR ALKENYL-4-AMINOPICOLINATES AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2004-10-21 | — | — | WO | disclosed |
| US-20040198608-A1 | 6-Alkyl or alkenyl-4-aminopicolinates and their use as herbicides | CORTEVA AGRISCIENCE LLC | 2004-10-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040198608-A1 | 6-Alkyl or alkenyl-4-aminopicolinates and their use as herbicides | AADAC, AASDHPPT, AADAT | TDP1 3420/4885HCAR2 267/4885ALDH1A1 650/4885 |
| US-20170042152-A1 | SAFENED HERBICIDAL COMPOSITIONS COMPRISING PYRIDINE CARBOXYLIC ACIDS | DDT, CYP4X1, IDH2 | TDP1 1942/4885HCAR2 128/4885ALDH1A1 716/4885 |
| US-20170042151-A1 | SAFENED HERBICIDAL COMPOSITIONS COMPRISING PYRIDINE CARBOXYLIC ACIDS | DDT, PPA1, CYP4Z1 | TDP1 1397/4885HCAR2 41/4885ALDH1A1 467/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.