Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | PLAU | P00749 | 2/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.31 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.30 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ASPH | Q12797 | 1/20 | 0.30 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30151452 | 1.00 | TDP1 (0.55) | TDP1PLAUHCAR2KEAP1NFE2L2 | |
| SCHEMBL11026035 | 0.86 | TDP1 (0.38) | TDP1PLAU | |
| SCHEMBL26172206 | 0.84 | TDP1 (0.37) | TDP1PLAU | |
| SCHEMBL2343868 | 0.83 | TDP1 (0.37) | TDP1PLAUHCAR2KDM4EASPH | |
| SCHEMBL1425504 | 0.83 | TDP1 (0.66) | TDP1PLAUHCAR2 | |
| SCHEMBL1424187 | 0.81 | TDP1 (0.69) | TDP1PLAUHCAR2KEAP1NFE2L2 | |
| SCHEMBL30151455 | 0.81 | TDP1 (0.36) | TDP1PLAUHCAR2KDM4EASPH | |
| SCHEMBL21806481 | 0.81 | TDP1 (0.36) | TDP1PLAUHCAR2KDM4EASPH | |
| SCHEMBL29928384 | 0.81 | TDP1 (0.69) | TDP1PLAUHCAR2KEAP1NFE2L2 | |
| SCHEMBL11024814 | 0.80 | NPSR1 (0.41) | TDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12624005-B2 | Synthesis of 4-amino-6-(heterocyclic)picolinates | CORTEVA AGRISCIENCE LLC (US) | 2026-05-12 | — | — | US | claimed |
| US-20230357155-A1 | IMPROVED SYNTHESIS OF 4-AMINO-6-(HETEROCYCLIC)PICOLINATES | CORTEVA AGRISCIENCE LLC (US) | 2023-11-09 | — | — | US | claimed |
| EP-4121414-A1 | IMPROVED SYNTHESIS OF 4-AMINO-6-(HETEROCYCLIC)PICOLINATES | Corteva Agriscience LLC (US) | 2023-01-25 | — | — | EP | claimed |
| CN-115279737-A | Improved synthesis of 4-amino-6- (heterocyclic) picolinates | 科迪华农业科技有限责任公司 | 2022-11-01 | — | — | CN | claimed |
| WO-2021188639-A1 | IMPROVED SYNTHESIS OF 4-AMINO-6-(HETEROCYCLIC)PICOLINATES | CORTEVA AGRISCIENCE LLC (US) | 2021-09-23 | — | — | WO | claimed |
| US-12624005-B2 | Synthesis of 4-amino-6-(heterocyclic)picolinates | CORTEVA AGRISCIENCE LLC (US) | 2026-05-12 | — | — | US | disclosed |
| US-12017993-B2 | Preparation of halogen analogs of picloram | CORTEVA AGRISCIENCE LLC (US) | 2024-06-25 | — | — | US | disclosed |
| US-20230357155-A1 | IMPROVED SYNTHESIS OF 4-AMINO-6-(HETEROCYCLIC)PICOLINATES | CORTEVA AGRISCIENCE LLC (US) | 2023-11-09 | — | — | US | disclosed |
| US-20230357155-A1 | IMPROVED SYNTHESIS OF 4-AMINO-6-(HETEROCYCLIC)PICOLINATES | CORTEVA AGRISCIENCE LLC (US) | 2023-11-09 | — | — | US | disclosed |
| US-20230357155-A1 | IMPROVED SYNTHESIS OF 4-AMINO-6-(HETEROCYCLIC)PICOLINATES | CORTEVA AGRISCIENCE LLC (US) | 2023-11-09 | — | — | US | disclosed |
| US-20230174490-A1 | IMPROVED SYNTHESIS OF 6-ARYL-4-AMINOPICOLINATES | CORTEVA AGRISCIENCE LLC (US) | 2023-06-08 | — | — | US | disclosed |
| US-20230174490-A1 | IMPROVED SYNTHESIS OF 6-ARYL-4-AMINOPICOLINATES | CORTEVA AGRISCIENCE LLC (US) | 2023-06-08 | — | — | US | disclosed |
| WO-2021188639-A1 | IMPROVED SYNTHESIS OF 4-AMINO-6-(HETEROCYCLIC)PICOLINATES | CORTEVA AGRISCIENCE LLC (US) | 2021-09-23 | — | — | WO | disclosed |
| WO-2021188654-A1 | IMPROVED SYNTHESIS OF 6-ARYL-4-AMINOPICOLINATES | CORTEVA AGRISCIENCE LLC (US) | 2021-09-23 | — | — | WO | disclosed |
| WO-2021188639-A1 | IMPROVED SYNTHESIS OF 4-AMINO-6-(HETEROCYCLIC)PICOLINATES | CORTEVA AGRISCIENCE LLC (US) | 2021-09-23 | — | — | WO | disclosed |
| WO-2021188654-A1 | IMPROVED SYNTHESIS OF 6-ARYL-4-AMINOPICOLINATES | CORTEVA AGRISCIENCE LLC (US) | 2021-09-23 | — | — | WO | disclosed |
| EP-3853205-A1 | PREPARATION OF HALOGEN ANALOGS OF PICLORAM | Corteva Agriscience LLC (US) | 2021-07-28 | — | — | EP | disclosed |
| CN-113015721-A | Preparation of picloram halogen analogs | 科迪华农业科技有限责任公司 | 2021-06-22 | — | — | CN | disclosed |
| WO-2020061146-A1 | PREPARATION OF HALOGEN ANALOGS OF PICLORAM | DOW AGROSCIENCES LLC (US) | 2020-03-26 | — | — | WO | disclosed |
| WO-2020061146-A1 | PREPARATION OF HALOGEN ANALOGS OF PICLORAM | DOW AGROSCIENCES LLC (US) | 2020-03-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230357155-A1 | IMPROVED SYNTHESIS OF 4-AMINO-6-(HETEROCYCLIC)PICOLINATES | APC, PPOX, ALAD | TDP1 1950/4885PLAU 3007/4885HCAR2 2382/4885 |
| US-12624005-B2 | Synthesis of 4-amino-6-(heterocyclic)picolinates | CLIC1, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, HCCS | TDP1 3832/4885PLAU 4740/4885HCAR2 83/4885 |
| US-20230174490-A1 | IMPROVED SYNTHESIS OF 6-ARYL-4-AMINOPICOLINATES | AAAS, AADAC, NPEPPS | TDP1 3412/4885PLAU 3655/4885HCAR2 1309/4885 |
| US-12017993-B2 | Preparation of halogen analogs of picloram | PBRM1, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, PHF6 | TDP1 2796/4885PLAU 3088/4885HCAR2 922/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.