Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 7/20 | 0.35 |
| ▸ | HTR2A | P28223 | 7/20 | 0.35 |
| ▸ | DRD3 | P35462 | 7/20 | 0.35 |
| ▸ | AXL | P30530 | 1/20 | 0.34 |
| ▸ | PHGDH | O43175 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29927588 | 0.75 | AXL (0.51) | HTR2CAXLALDH1A1 | |
| SCHEMBL29928245 | 0.69 | ATM (0.49) | KDM4EALDH1A1 | |
| SCHEMBL557772 | 0.67 | NOS3 (0.43) | HTR2CDYRK1A | |
| SCHEMBL15971536 | 0.66 | HTR2C (0.73) | HTR2CDRD2HTR2ADRD3PHGDH | |
| SCHEMBL15971496 | 0.65 | HTR2C (0.71) | HTR2CDRD2HTR2ADRD3PHGDH | |
| SCHEMBL3679735 | 0.64 | HTR2C (0.69) | HTR2CDRD2HTR2ADRD3PHGDH | |
| SCHEMBL4935508 | 0.64 | HTR2C (0.69) | HTR2CDRD2HTR2ADRD3PHGDH | |
| SCHEMBL1601087 | 0.64 | HTR2C (0.69) | HTR2CDRD2HTR2ADRD3PHGDH | |
| SCHEMBL29928021 | 0.63 | KDR (0.50) | HTR2CDRD2HTR2AAXLALDH1A1 | |
| SCHEMBL1026755 | 0.62 | HTR2C (1.00) | HTR2CDYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110551105-B | Substituted triazoles useful as AXL inhibitors | 里格尔制药公司 | 2022-10-18 | — | — | CN | claimed |
| CN-110551105-B | Substituted triazoles useful as AXL inhibitors | 里格尔制药公司 | 2022-10-18 | — | — | CN | disclosed |