Dihydromorin

Dihydromorin

SCHEMBL29929436

O=C1c2c(O)cc(O)cc2OC(c2ccc(O)cc2O)C1O

nearest known ligand 0.72

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.65
CYP3A4 P08684 4/20 0.65
ALOX15 P16050 4/20 0.65
RECQL P46063 3/20 0.65
MEN1 O00255 3/20 0.65
KMT2A Q03164 3/20 0.65
HSD17B10 Q99714 3/20 0.65
SOST Q9BQB4 2/20 0.65
POLB P06746 2/20 0.65
KDM4E B2RXH2 2/20 0.65
GAA P10253 2/20 0.65
ALOX12 P18054 2/20 0.65
HIF1A Q16665 2/20 0.65
CYP1A2 P05177 1/20 0.65
NFKB1 P19838 1/20 0.65
MAPK1 P28482 1/20 0.65
TDP1 Q9NUW8 2/20 0.64
SYNJ2 O15056 1/20 0.64
APP P05067 1/20 0.64
XDH P47989 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dihydromorin SCHEMBL29397807 1.00 MAPT (0.65) MAPTCYP3A4ALOX15RECQLMEN1
Dihydromorin SCHEMBL10174295 1.00 MAPT (0.65) MAPTCYP3A4ALOX15RECQLMEN1
Dihydromorin SCHEMBL29929680 1.00 MAPT (0.65) MAPTCYP3A4ALOX15RECQLMEN1
Dihydromorin SCHEMBL6819045 1.00 MAPT (0.65) MAPTCYP3A4ALOX15RECQLMEN1
SCHEMBL15197248 0.89 MAPT (0.60) MAPTCYP3A4ALOX15RECQLMEN1
SCHEMBL27796495 0.89 MAPT (0.65) MAPTCYP3A4ALOX15RECQLMEN1
SCHEMBL3362576 0.89 MAPT (0.65) MAPTCYP3A4ALOX15RECQLMEN1
SCHEMBL15530038 0.86 SOST (0.65) MAPTCYP3A4ALOX15RECQLMEN1
SCHEMBL28841492 0.84 MAPT (0.67) MAPTCYP3A4ALOX15RECQLMEN1
SCHEMBL27222267 0.84 MAPT (0.67) MAPTCYP3A4ALOX15RECQLMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023064318-A1 BIPHASIC COMPOSITIONS COMPRISING ONE OR BOTH OF CARBONATE AND PHOSPHATE Natural Extraction Systems, LLC (US) 2023-04-20 WO claimed
WO-2022182527-A1 COMPOSITIONS AND METHODS RELATED TO PHARMACEUTICAL EXCIPIENTS Natural Extraction Systems, LLC (US) 2022-09-01 WO claimed
WO-2023064318-A1 BIPHASIC COMPOSITIONS COMPRISING ONE OR BOTH OF CARBONATE AND PHOSPHATE Natural Extraction Systems, LLC (US) 2023-04-20 WO disclosed