Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.65 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.65 |
| ▸ | RECQL | P46063 | 3/20 | 0.65 |
| ▸ | MEN1 | O00255 | 3/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.65 |
| ▸ | SOST | Q9BQB4 | 2/20 | 0.65 |
| ▸ | POLB | P06746 | 2/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.65 |
| ▸ | GAA | P10253 | 2/20 | 0.65 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.65 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.65 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.64 |
| ▸ | SYNJ2 | O15056 | 1/20 | 0.64 |
| ▸ | APP | P05067 | 1/20 | 0.64 |
| ▸ | XDH | P47989 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dihydromorin SCHEMBL29397807 | 1.00 | MAPT (0.65) | MAPTCYP3A4ALOX15RECQLMEN1 | |
| Dihydromorin SCHEMBL29929436 | 1.00 | MAPT (0.65) | MAPTCYP3A4ALOX15RECQLMEN1 | |
| Dihydromorin SCHEMBL29929680 | 1.00 | MAPT (0.65) | MAPTCYP3A4ALOX15RECQLMEN1 | |
| Dihydromorin SCHEMBL6819045 | 1.00 | MAPT (0.65) | MAPTCYP3A4ALOX15RECQLMEN1 | |
| SCHEMBL15197248 | 0.89 | MAPT (0.60) | MAPTCYP3A4ALOX15RECQLMEN1 | |
| SCHEMBL27796495 | 0.89 | MAPT (0.65) | MAPTCYP3A4ALOX15RECQLMEN1 | |
| SCHEMBL3362576 | 0.89 | MAPT (0.65) | MAPTCYP3A4ALOX15RECQLMEN1 | |
| SCHEMBL15530038 | 0.86 | SOST (0.65) | MAPTCYP3A4ALOX15RECQLMEN1 | |
| SCHEMBL28841492 | 0.84 | MAPT (0.67) | MAPTCYP3A4ALOX15RECQLMEN1 | |
| SCHEMBL27222267 | 0.84 | MAPT (0.67) | MAPTCYP3A4ALOX15RECQLMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11771679-B2 | Composition containing hesperetin and synergistic hypoglycemic application thereof | ZHENGZHOU FRUIT RESEARCH INSTITUTE, CHINESE ACADEMY OF AGRICULTURAL SCIENCES (CN) | 2023-10-03 | — | — | US | disclosed |
| US-11771679-B2 | Composition containing hesperetin and synergistic hypoglycemic application thereof | ZHENGZHOU FRUIT RESEARCH INSTITUTE, CHINESE ACADEMY OF AGRICULTURAL SCIENCES (CN) | 2023-10-03 | — | — | US | disclosed |
| US-11753388-B2 | Composition for inhibiting alpha-glucosidase and application thereof | ZHENGZHOU FRUIT RESEARCH INSTITUTE, CHINESE ACADEMY OF AGRICULTURAL SCIENCES (CN) | 2023-09-12 | — | — | US | disclosed |
| US-11753388-B2 | Composition for inhibiting alpha-glucosidase and application thereof | ZHENGZHOU FRUIT RESEARCH INSTITUTE, CHINESE ACADEMY OF AGRICULTURAL SCIENCES (CN) | 2023-09-12 | — | — | US | disclosed |
| CN-111630041-B | Synthesis of morin and morin derivatives | 奥萨特有限公司 | 2023-08-15 | — | — | CN | disclosed |
| US-20230125518-A1 | COMPOSITION CONTAINING HESPERETIN AND SYNERGISTIC HYPOGLYCEMIC APPLICATION THEREOF | ZHENGZHOU FRUIT RESEARCH INSTITUTE, CHINESE ACADEMY OF AGRICULTURAL SCIENCES (CN) | 2023-04-27 | — | — | US | disclosed |
| US-20230125518-A1 | COMPOSITION CONTAINING HESPERETIN AND SYNERGISTIC HYPOGLYCEMIC APPLICATION THEREOF | ZHENGZHOU FRUIT RESEARCH INSTITUTE, CHINESE ACADEMY OF AGRICULTURAL SCIENCES (CN) | 2023-04-27 | — | — | US | disclosed |
| US-20230129488-A1 | COMPOSITION FOR INHIBITING ALPHA-GLUCOSIDASE AND APPLICATION THEREOF | ZHENGZHOU FRUIT RESEARCH INSTITUTE, CHINESE ACADEMY OF AGRICULTURAL SCIENCES (CN) | 2023-04-27 | — | — | US | disclosed |
| US-20230129488-A1 | COMPOSITION FOR INHIBITING ALPHA-GLUCOSIDASE AND APPLICATION THEREOF | ZHENGZHOU FRUIT RESEARCH INSTITUTE, CHINESE ACADEMY OF AGRICULTURAL SCIENCES (CN) | 2023-04-27 | — | — | US | disclosed |
| EP-2603594-B1 | COMPOSITIONS COMPRISING A POLYPEPTIDE HAVING CELLULOLYTIC ENHANCING ACTIVITY AND A BICYCLIC COMPOUND AND USES THEREOF | NOVOZYMES INC (US) | 2018-04-25 | — | — | EP | disclosed |
| US-9458483-B2 | Compositions comprising a polypeptide having cellulolytic enhancing activity and a bicyclic compound and uses thereof | NOVOZYMES, INC. (US) | 2016-10-04 | — | — | US | disclosed |
| US-20150307908-A1 | Compositions Comprising A Polypeptide Having Cellulolytic Enhancing Activity And A Bicyclic Compound And Uses Thereof | UNITED STATES DEPARTMENT OF ENERGY | 2015-10-29 | — | — | US | disclosed |
| US-9057086-B2 | Compositions comprising a polypeptide having cellulolytic enhancing activity and a bicycle compound and uses thereof | NOVOZYMES, INC. (US) | 2015-06-16 | — | — | US | disclosed |
| US-20140018552-A1 | USE OF COMPOUNDS ISOLATED FROM MORUS BARK | DONG WHA PHARM. CO., LTD. (KR) | 2014-01-16 | — | — | US | disclosed |
| US-20140018552-A1 | USE OF COMPOUNDS ISOLATED FROM MORUS BARK | DONG WHA PHARM. CO., LTD. (KR) | 2014-01-16 | — | — | US | disclosed |
| US-20130217077-A1 | Compositions Comprising A Polypeptide Having Cellulolytic Enhancing Activity And A Bicyclic Compound And Uses Thereof | NOVOZYMES, INC. (US) | 2013-08-22 | — | — | US | disclosed |
| WO-2012021401-A1 | COMPOSITIONS COMPRISING A POLYPEPTIDE HAVING CELLULOLYTIC ENHANCING ACTIVITY AND A BICYCLIC COMPOUND AND USES THEREOF | NOVOZYMES, INC. (US) | 2012-02-16 | — | — | WO | disclosed |
| US-20100178282-A1 | COMPOUNDS AND METHODS FOR THE DIAGNOSIS AND TREATMENT OF AMYLOID ASSOCIATED DISEASES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2010-07-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230125518-A1 | COMPOSITION CONTAINING HESPERETIN AND SYNERGISTIC HYPOGLYCEMIC APPLICATION THEREOF | GANAB, GANC, HES1 | MAPT 4188/4885CYP3A4 248/4885ALOX15 1833/4885 |
| US-20140018552-A1 | USE OF COMPOUNDS ISOLATED FROM MORUS BARK | AGER, MORF4L1, HNRNPF | MAPT 2794/4885CYP3A4 3690/4885ALOX15 184/4885 |
| US-11753388-B2 | Composition for inhibiting alpha-glucosidase and application thereof | GANAB, MGAM, GANC | MAPT 2714/4885CYP3A4 100/4885ALOX15 3092/4885 |
| US-20100178282-A1 | COMPOUNDS AND METHODS FOR THE DIAGNOSIS AND TREATMENT OF AMYLOID ASSOCIATED DISEASES | APP, APBA1, BACE1 | MAPT 7/4885CYP3A4 4536/4885ALOX15 2115/4885 |
| US-11771679-B2 | Composition containing hesperetin and synergistic hypoglycemic application thereof | GANAB, GANC, HES1 | MAPT 4188/4885CYP3A4 248/4885ALOX15 1833/4885 |
| US-20230129488-A1 | COMPOSITION FOR INHIBITING ALPHA-GLUCOSIDASE AND APPLICATION THEREOF | GANAB, MGAM, GANC | MAPT 2714/4885CYP3A4 100/4885ALOX15 3092/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.