Dihydromorin

Dihydromorin

SCHEMBL6819045

O=C1c2c(O)cc(O)cc2O[C@H](c2ccc(O)cc2O)[C@H]1O

nearest known ligand 0.72

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.65
CYP3A4 P08684 4/20 0.65
ALOX15 P16050 4/20 0.65
RECQL P46063 3/20 0.65
MEN1 O00255 3/20 0.65
KMT2A Q03164 3/20 0.65
HSD17B10 Q99714 3/20 0.65
SOST Q9BQB4 2/20 0.65
POLB P06746 2/20 0.65
KDM4E B2RXH2 2/20 0.65
GAA P10253 2/20 0.65
ALOX12 P18054 2/20 0.65
HIF1A Q16665 2/20 0.65
CYP1A2 P05177 1/20 0.65
NFKB1 P19838 1/20 0.65
MAPK1 P28482 1/20 0.65
TDP1 Q9NUW8 2/20 0.64
SYNJ2 O15056 1/20 0.64
APP P05067 1/20 0.64
XDH P47989 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dihydromorin SCHEMBL29397807 1.00 MAPT (0.65) MAPTCYP3A4ALOX15RECQLMEN1
Dihydromorin SCHEMBL29929436 1.00 MAPT (0.65) MAPTCYP3A4ALOX15RECQLMEN1
Dihydromorin SCHEMBL10174295 1.00 MAPT (0.65) MAPTCYP3A4ALOX15RECQLMEN1
Dihydromorin SCHEMBL29929680 1.00 MAPT (0.65) MAPTCYP3A4ALOX15RECQLMEN1
SCHEMBL15197248 0.89 MAPT (0.60) MAPTCYP3A4ALOX15RECQLMEN1
SCHEMBL27796495 0.89 MAPT (0.65) MAPTCYP3A4ALOX15RECQLMEN1
SCHEMBL3362576 0.89 MAPT (0.65) MAPTCYP3A4ALOX15RECQLMEN1
SCHEMBL15530038 0.86 SOST (0.65) MAPTCYP3A4ALOX15RECQLMEN1
SCHEMBL28841492 0.84 MAPT (0.67) MAPTCYP3A4ALOX15RECQLMEN1
SCHEMBL27222267 0.84 MAPT (0.67) MAPTCYP3A4ALOX15RECQLMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240315965-A1 COMPOSITIONS AND METHODS RELATED TO PHARMACEUTICAL EXCIPIENTS Natural Extraction Systems, LLC (US) 2024-09-26 US claimed
WO-2022182527-A1 COMPOSITIONS AND METHODS RELATED TO PHARMACEUTICAL EXCIPIENTS Natural Extraction Systems, LLC (US) 2022-09-01 WO claimed
US-20240016777-A1 COMPOUNDS AND METHODS FOR TREATING VIRAL INFECTIONS BETH ISRAEL DEACONESS MEDICAL CENTER, INC. 2024-01-18 US disclosed
US-20240016777-A1 COMPOUNDS AND METHODS FOR TREATING VIRAL INFECTIONS BETH ISRAEL DEACONESS MEDICAL CENTER, INC. 2024-01-18 US disclosed
CN-113476438-B Hypoglycemic composition containing dihydro morin and application thereof 中国农业科学院郑州果树研究所 2022-09-09 CN disclosed
CN-113476438-A Hypoglycemic composition containing dihydro morin and application thereof 中国农业科学院郑州果树研究所 2021-10-08 CN disclosed
CN-105641270-A Pharmaceutical composition for treating cerebral thrombosis and preparation method thereof 济南星懿医药技术有限公司 2016-06-08 CN disclosed
CN-105168431-A Medicine composition for treating coronary heart disease and angina JINAN XINGYI MED TECH CO LTD 2015-12-23 CN disclosed
CN-105031001-A Medicine composition for treating cataract JINAN XINGYI MED TECH CO LTD 2015-11-11 CN disclosed
CN-104523701-A Pharmaceutical composition for treating Aids JINAN XINGYI MED TECH CO LTD 2015-04-22 CN disclosed
CN-104523732-A Pharmaceutical composition for treating phthisis JINAN XINGYI MED TECH CO LTD 2015-04-22 CN disclosed
CN-104523731-A Pharmaceutical composition for treating pulmonary tuberculosis JINAN XINGYI MED TECH CO LTD 2015-04-22 CN disclosed
CN-104523729-A Pharmaceutical composition for treating phthisis JINAN XINGYI MED TECH CO LTD 2015-04-22 CN disclosed
CN-104523721-A Anticancer pharmaceutical composition JINAN XINGYI MED TECH CO LTD 2015-04-22 CN disclosed
CN-104510741-A Pharmaceutical composition for treating AIDS JINAN XINGYI MED TECH CO LTD 2015-04-15 CN disclosed
CN-104510739-A Pharmaceutical composition for treating AIDS JINAN XINGYI MED TECH CO LTD 2015-04-15 CN disclosed
CN-104510740-A Pharmaceutical composition for treating AIDS JINAN XINGYI MED TECH CO LTD 2015-04-15 CN disclosed
CN-104510742-A Pharmaceutical composition for treating AIDS JINAN XINGYI MED TECH CO LTD 2015-04-15 CN disclosed
US-6737439-B2 ACTIVE CANCER CHEMOPREVENTATIVE AND TREATING AGENTS IN MAMMALS, INCLUDING HUMANS THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS 2004-05-18 US disclosed
US-20030125377-A1 Aromatase inhibitors from Broussonetia papyrifera BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS THE 2003-07-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030125377-A1 Aromatase inhibitors from Broussonetia papyrifera CYP19A1, HSD17B11, CYP17A1 MAPT 3960/4885CYP3A4 38/4885ALOX15 717/4885
US-20240016777-A1 COMPOUNDS AND METHODS FOR TREATING VIRAL INFECTIONS THPO, SERPINB1, SERPINC1 MAPT 2717/4885CYP3A4 1420/4885ALOX15 457/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.