Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.97 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.75 |
| ▸ | ADORA2A | P29274 | 8/20 | 0.72 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.68 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.68 |
| ▸ | PI4KA | P42356 | 2/20 | 0.58 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.58 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.58 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.58 |
| ▸ | ADCY5 | O95622 | 3/20 | 0.52 |
| ▸ | BACE1 | P56817 | 1/20 | 0.50 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29087571 | 0.87 | ALDH1A1 (0.79) | ALDH1A1ADCY1ADORA2AADORA1ADORA2B | |
| SCHEMBL29087636 | 0.87 | ADCY1 (0.97) | ALDH1A1ADCY1ADORA2AADORA1ADORA2B | |
| SCHEMBL4551803 | 0.86 | ADORA2A (0.91) | ALDH1A1ADORA2AADORA1ADORA2BPI4KA | |
| Nb-001 SCHEMBL29886392 | 0.86 | ADCY1 (1.00) | ALDH1A1ADCY1ADORA2AADORA1ADORA2B | |
| Nb-001 SCHEMBL13697544 | 0.86 | ADCY1 (1.00) | ALDH1A1ADCY1ADORA2AADORA1ADORA2B | |
| SCHEMBL23228230 | 0.85 | ADORA2A (0.88) | ALDH1A1ADCY1ADORA2AADORA1ADORA2B | |
| SCHEMBL28228476 | 0.85 | ADORA2A (0.88) | ALDH1A1ADORA2AADORA1ADORA2BPI4KA | |
| SCHEMBL1741560 | 0.85 | ADORA2A (0.88) | ALDH1A1ADCY1ADORA2AADORA1ADORA2B | |
| SCHEMBL21469779 | 0.85 | ADORA2A (0.88) | ALDH1A1ADCY1ADORA2AADORA1ADORA2B | |
| SCHEMBL28176129 | 0.85 | ADORA2A (0.88) | ALDH1A1ADORA2AADORA1ADORA2BPI4KA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115998745-A | Use of an adenylate cyclase inhibitor NB001 in the manufacture of a medicament for the treatment of pain and anxiety associated with Parkinson's disease | 永展控股有限公司 | 2023-04-25 | — | — | CN | claimed |
| CN-115990167-A | Application of adenylate cyclase inhibitor NB001 in preparation of medicine for treating migraine and anxiety | 永展控股有限公司 | 2023-04-21 | — | — | CN | claimed |
| CN-114984020-A | Use of adenylate cyclase inhibitors for the treatment of epilepsy and related disorders | 永展控股有限公司 | 2022-09-02 | — | — | CN | claimed |
| CN-114984020-B | Use of adenylate cyclase inhibitors for the treatment of epilepsy and related disorders | 永展控股有限公司 | 2024-08-30 | — | — | CN | disclosed |
| CN-115998745-B | Use of an adenylate cyclase inhibitor NB001 in the manufacture of a medicament for the treatment of pain and anxiety associated with Parkinson's disease | 永展控股有限公司 | 2024-05-14 | — | — | CN | disclosed |
| CN-115998745-B | Use of an adenylate cyclase inhibitor NB001 in the manufacture of a medicament for the treatment of pain and anxiety associated with Parkinson's disease | 永展控股有限公司 | 2024-05-14 | — | — | CN | disclosed |
| CN-115998745-A | Use of an adenylate cyclase inhibitor NB001 in the manufacture of a medicament for the treatment of pain and anxiety associated with Parkinson's disease | 永展控股有限公司 | 2023-04-25 | — | — | CN | disclosed |
| CN-115998745-A | Use of an adenylate cyclase inhibitor NB001 in the manufacture of a medicament for the treatment of pain and anxiety associated with Parkinson's disease | 永展控股有限公司 | 2023-04-25 | — | — | CN | disclosed |
| CN-115990167-A | Application of adenylate cyclase inhibitor NB001 in preparation of medicine for treating migraine and anxiety | 永展控股有限公司 | 2023-04-21 | — | — | CN | disclosed |
| CN-115990167-A | Application of adenylate cyclase inhibitor NB001 in preparation of medicine for treating migraine and anxiety | 永展控股有限公司 | 2023-04-21 | — | — | CN | disclosed |
| CN-114984020-A | Use of adenylate cyclase inhibitors for the treatment of epilepsy and related disorders | 永展控股有限公司 | 2022-09-02 | — | — | CN | disclosed |