Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPFFR1 | Q9GZQ6 | 2/20 | 0.50 |
| ▸ | NPFFR2 | Q9Y5X5 | 2/20 | 0.50 |
| ▸ | UBE2M | P61081 | 1/20 | 0.43 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.43 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.39 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | SHH | Q15465 | 1/20 | 0.37 |
| ▸ | SMO | Q99835 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28348073 | 0.92 | NPFFR1 (0.45) | NPFFR1NPFFR2UBE2MDCUN1D1CXCR4 | |
| SCHEMBL29930039 | 0.90 | ATM (0.41) | NPFFR1NPFFR2UBE2MDCUN1D1HSD11B1 | |
| SCHEMBL13841889 | 0.85 | HSD11B1 (0.50) | HSD11B1CYP3A4NR1H4OPRM1ALDH1A1 | |
| SCHEMBL2822792 | 0.85 | HSD11B1 (0.50) | HSD11B1CYP3A4NR1H4OPRM1ALDH1A1 | |
| SCHEMBL28348072 | 0.82 | HSD11B1 (0.42) | NPFFR1NPFFR2HSD11B1SLC16A3SLC16A1 | |
| SCHEMBL28345159 | 0.81 | HSD11B1 (0.40) | NPFFR1NPFFR2HSD11B1SLC16A3SLC16A1 | |
| SCHEMBL2824379 | 0.76 | HSD11B1 (0.52) | HSD11B1NR1H4OPRM1 | |
| SCHEMBL13841892 | 0.76 | HSD11B1 (0.52) | HSD11B1NR1H4OPRM1 | |
| SCHEMBL28345021 | 0.76 | NPFFR1 (0.79) | NPFFR1NPFFR2CXCR4CYP3A4SMN1; SMN2 | |
| SCHEMBL2818863 | 0.75 | HTR2A (0.44) | HSD11B1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12390446-B2 | Proline-based neuropeptide FF receptor modulators | RESEARCH TRIANGLE INSTITUTE (US) | 2025-08-19 | — | — | US | disclosed |
| US-20240058303-A1 | PROLINE-BASED NEUROPEPTIDE FF RECEPTOR MODULATORS | RES TRIANGLE INST (US) | 2024-02-22 | — | — | US | disclosed |
| US-11826350-B2 | Proline-based neuropeptide FF receptor modulators | RESEARCH TRIANGLE INSTITUTE (US) | 2023-11-28 | — | — | US | disclosed |
| US-20230091922-A1 | PROLINE-BASED NEUROPEPTIDE FF RECEPTOR MODULATORS | RES TRIANGLE INST (US) | 2023-03-23 | — | — | US | disclosed |
| US-11491136-B2 | Proline-based neuropeptide FF receptor modulators | RESEARCH TRIANGLE INSTITUTE (US) | 2022-11-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11491136-B2 | Proline-based neuropeptide FF receptor modulators | NPFFR1, NPFFR2, NPBWR1 | NPFFR1 1/4885NPFFR2 2/4885UBE2M 4704/4885 |
| US-12390446-B2 | Proline-based neuropeptide FF receptor modulators | NPFFR1, NPFFR2, NPBWR1 | NPFFR1 1/4885NPFFR2 2/4885UBE2M 4704/4885 |
| US-11826350-B2 | Proline-based neuropeptide FF receptor modulators | NPFFR1, NPFFR2, NPBWR1 | NPFFR1 1/4885NPFFR2 2/4885UBE2M 4704/4885 |
| US-20240058303-A1 | PROLINE-BASED NEUROPEPTIDE FF RECEPTOR MODULATORS | NPFFR1, NPFFR2, NPBWR1 | NPFFR1 1/4885NPFFR2 2/4885UBE2M 4704/4885 |
| US-20230091922-A1 | PROLINE-BASED NEUROPEPTIDE FF RECEPTOR MODULATORS | NPFFR1, NPFFR2, NPBWR1 | NPFFR1 1/4885NPFFR2 2/4885UBE2M 4704/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.