Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.40 |
| ▸ | KLKB1 | P03952 | 4/20 | 0.38 |
| ▸ | CASR | P41180 | 2/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23327453 | 1.00 | LMNA (0.42) | LMNATRPV1KLKB1CASRHCAR2 | |
| SCHEMBL23351083 | 0.93 | LMNA (0.47) | LMNATRPV1CASRHCAR2KMT2A | |
| SCHEMBL23327491 | 0.90 | TRPV1 (0.46) | TRPV1KMT2AKDM4EMEN1ALDH1A1 | |
| SCHEMBL23327703 | 0.82 | KDM4E (0.36) | TRPV1KMT2AKDM4EMEN1ALDH1A1 | |
| SCHEMBL23327537 | 0.81 | NR3C2 (0.38) | KMT2AKDM4EMEN1ALDH1A1 | |
| SCHEMBL23327500 | 0.75 | ALDH1A1 (0.43) | KMT2AKDM4EALDH1A1 | |
| SCHEMBL23351205 | 0.74 | ALDH1A1 (0.35) | LMNAKMT2AKDM4EMEN1ALDH1A1 | |
| SCHEMBL26098304 | 0.73 | PTPN1 (0.49) | KMT2AKDM4EMEN1ALDH1A1 | |
| SCHEMBL21811192 | 0.69 | KDM4E (0.44) | LMNAKDM4EALDH1A1 | |
| SCHEMBL23327454 | 0.68 | MAPT (0.42) | LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4054581-A1 | TYK2 PSEUDOKINASE LIGANDS | Ventyx Biosciences, Inc. (US) | 2022-09-14 | — | — | EP | disclosed |