Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | IKBKB | O14920 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | F7 | P08709 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CCR1 | P32246 | 2/20 | 0.38 |
| ▸ | CCR5 | P51681 | 2/20 | 0.38 |
| ▸ | CCR8 | P51685 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30761191 | 0.88 | IKBKB (0.49) | NPC1TP53SMN1; SMN2HPGDRAB9A | |
| SCHEMBL30775055 | 0.80 | KDM4E (0.48) | NPC1TP53SMN1; SMN2HPGDRAB9A | |
| SCHEMBL3385678 | 0.80 | KDM4E (0.48) | NPC1TP53SMN1; SMN2HPGDRAB9A | |
| SCHEMBL20780897 | 0.79 | NPC1 (0.45) | NPC1TP53SMN1; SMN2HPGDRAB9A | |
| SCHEMBL7910798 | 0.79 | KDM4E (0.46) | NPC1TP53SMN1; SMN2HPGDRAB9A | |
| SCHEMBL20773709 | 0.77 | L3MBTL1 (0.46) | NPC1TP53SMN1; SMN2HPGDRAB9A | |
| SCHEMBL30775039 | 0.77 | L3MBTL1 (0.46) | NPC1TP53SMN1; SMN2HPGDRAB9A | |
| SCHEMBL10262377 | 0.75 | KDM4E (0.48) | NPC1TP53SMN1; SMN2HPGDRAB9A | |
| Hydrochloric Acid SCHEMBL31267313 | 0.69 | KDM4E (0.45) | NPC1TP53SMN1; SMN2HPGDRAB9A | |
| SCHEMBL19700489 | 0.69 | PRSS1 (0.42) | RAB9AIKBKBGRM5KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114989173-A | Imidazole compound, pharmaceutical composition and application thereof | 广州市恒诺康医药科技有限公司 | 2022-09-02 | — | — | CN | disclosed |