SCHEMBL29930948

SCHEMBL29930948

[2H]C([2H])(Br)C#C[Si](C)(C)C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24235 0.75
Phosphine SCHEMBL10964059 0.73
SCHEMBL3474495 0.73
SCHEMBL101567 0.71
SCHEMBL30823002 0.71
SCHEMBL8977890 0.67
SCHEMBL4822542 0.65
SCHEMBL9445689 0.65
SCHEMBL13101758 0.65
SCHEMBL16487278 0.64 RAB9A (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4740942-A1 AROMATIC AMIDE DERIVATIVE AND USE THEREOF HUAJIAN FUTURE (CHENGDU) TECHNOLOGY CO., LTD. (CN) 2026-05-13 EP disclosed
CN-119421874-A Aromatic amide derivative and application thereof in antitumor drugs 上海喆邺生物科技有限公司 2025-02-11 CN disclosed
WO-2025007811-A1 AROMATIC AMIDE DERIVATIVE AND USE THEREOF 成都华健未来科技有限公司 2025-01-09 WO disclosed
US-20240382477-A1 NITROGEN-CONTAINING HETEROCYCLIC PYRIDINE COMPOUND SHANGHAI ZHEYE BIOTECHNOLOGY CO. LTD. (CN) 2024-11-21 US disclosed
WO-2024002210-A1 AROMATIC AMIDE DERIVATIVE AND USE THEREOF IN ANTITUMOR DRUGS 上海喆邺生物科技有限公司 2024-01-04 WO disclosed
CN-117136058-A Nitrogen-containing heterocyclic pyridine compounds 上海喆邺生物科技有限公司 2023-11-28 CN disclosed
WO-2022233286-A1 NITROGEN-CONTAINING HETEROCYCLIC PYRIDINE COMPOUND 上海喆邺生物科技有限公司 2022-11-10 WO disclosed