Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRNP | P04156 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.40 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 5/20 | 0.37 |
| ▸ | LIMK1 | P53667 | 5/20 | 0.37 |
| ▸ | CDC7 | O00311 | 4/20 | 0.37 |
| ▸ | PLK4 | O00444 | 4/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 4/20 | 0.37 |
| ▸ | PRKD3 | O94806 | 4/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 4/20 | 0.37 |
| ▸ | INSR | P06213 | 4/20 | 0.37 |
| ▸ | CDK1 | P06493 | 4/20 | 0.37 |
| ▸ | PIM1 | P11309 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrazine SCHEMBL6691493 | 0.78 | MCL1 (0.42) | TSHRMAPK1RXFP1GSK3BALDH1A1 | |
| SCHEMBL4946672 | 0.77 | GSK3B (0.33) | GSK3B | |
| SCHEMBL978687 | 0.77 | MCL1 (0.45) | TSHRMAPK1RXFP1GSK3BALDH1A1 | |
| Hydrochloric Acid SCHEMBL7469372 | 0.75 | MCL1 (0.44) | TSHRMAPK1RXFP1GSK3BALDH1A1 | |
| SCHEMBL6696332 | 0.75 | OGG1 (0.51) | GSK3BCDC7GAAALDH1A1MAPT | |
| SCHEMBL7040413 | 0.73 | GSK3B (0.31) | GSK3B | |
| SCHEMBL23531531 | 0.72 | RAB9A (0.35) | PPARGGSK3BLIMK1CDC7PLK4 | |
| SCHEMBL13858020 | 0.70 | GSK3B (0.33) | GSK3BHDAC6 | |
| SCHEMBL25061794 | 0.69 | CHRM4 (0.38) | NPSR1RXFP1GAAALDH1A1MAPT | |
| SCHEMBL23560341 | 0.69 | MALT1 (0.35) | GSK3BGAAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115052869-A | Substituted thiophenecarboxamides and derivatives thereof | 拜耳公司 | 2022-09-13 | — | — | CN | disclosed |