Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | DAO | P14920 | 2/20 | 0.31 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL978687 | 0.80 | MCL1 (0.45) | GSK3BDAOGPR35MCL1 | |
| Hydrochloric Acid SCHEMBL7469372 | 0.78 | MCL1 (0.44) | GSK3BDAOGPR35MCL1 | |
| Hydrazine SCHEMBL6691493 | 0.76 | MCL1 (0.42) | GSK3BDAOGPR35MCL1 | |
| SCHEMBL25307067 | 0.71 | GSK3B (0.39) | GSK3BDAOMCL1 | |
| SCHEMBL13858020 | 0.68 | GSK3B (0.33) | GSK3B | |
| SCHEMBL18701567 | 0.66 | MCL1 (0.50) | DAOGPR35MCL1 | |
| SCHEMBL25176397 | 0.65 | DAO (0.39) | GSK3BDAOGPR35MCL1 | |
| SCHEMBL21612056 | 0.65 | ALDH1A1 (0.45) | DAOGPR35MCL1 | |
| SCHEMBL21612129 | 0.65 | GPR35 (0.46) | GSK3BDAOGPR35MCL1 | |
| SCHEMBL18701665 | 0.65 | BCKDK (0.41) | GSK3BDAOGPR35MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6613786-B2 | Treating urinary incontinence, asthma, irritable bowel syndrome or male erectile dysfunction | BRISTOL-MYERS SQUIBB COMPANY | 2003-09-02 | — | — | US | disclosed |
| US-20030144333-A1 | Thiophenyl triazol-3-one derivatives as smooth muscle relaxants | HEWAWASAM PIYASENA (US) | 2003-07-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030144333-A1 | Thiophenyl triazol-3-one derivatives as smooth muscle relaxants | PDE3A, ADRB2, ADRB3 | GSK3B 3398/4885DAO 3738/4885GPR35 43/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.