Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.42 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | NPY2R | P49146 | 2/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.35 |
| ▸ | PHGDH | O43175 | 1/20 | 0.35 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CKS1B | P61024 | 1/20 | 0.34 |
| ▸ | SKP1 | P63208 | 1/20 | 0.34 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30718184 | 0.91 | ACHE (0.49) | ACHEPTPN11DDB1CRBNBACE1 | |
| SCHEMBL27029481 | 0.91 | ACHE (0.49) | ACHEPTPN11DDB1CRBNBACE1 | |
| SCHEMBL5636609 | 0.78 | MEN1 (0.48) | MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL24851896 | 0.77 | GPR119 (0.50) | ACHEPTPN11BACE1MEN1KMT2A | |
| SCHEMBL29931648 | 0.77 | PIK3CA (0.44) | ACHEPTPN11GSK3BDYRK1A | |
| SCHEMBL27931713 | 0.75 | NPY2R (0.48) | NPY2RMEN1KMT2AMAPT | |
| SCHEMBL18153366 | 0.74 | MAPT (0.51) | MAPTSMN1; SMN2 | |
| SCHEMBL21815386 | 0.74 | GBA1 (0.51) | MEN1KMT2AMAPT | |
| SCHEMBL18162439 | 0.74 | ACHE (0.47) | ACHEPTPN11DDB1CRBNMEN1 | |
| SCHEMBL16147173 | 0.74 | ATR (0.45) | GSK3BDYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022194248-A1 | CTLA-4 SMALL MOLECULE DEGRADATION AGENT AND APPLICATION THEREOF | 苏州国匡医药科技有限公司 | 2022-09-22 | — | — | WO | disclosed |