Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | BPTF | Q12830 | 1/20 | 0.46 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.46 |
| ▸ | CDK2 | P24941 | 3/20 | 0.46 |
| ▸ | GALR2 | O43603 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | GALR1 | P47211 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18153299 | 0.88 | CCNE1 (0.48) | MAPTCCNE1CDK2GALR2GALR1 | |
| SCHEMBL18153314 | 0.88 | LMNA (0.66) | MAPTLMNABPTFCCNE1CDK2 | |
| SCHEMBL18162439 | 0.85 | ACHE (0.47) | MAPTLMNABPTFCCNE1CDK2 | |
| SCHEMBL18153312 | 0.84 | LMNA (0.49) | MAPTLMNABPTFCCNE1CDK2 | |
| SCHEMBL18153311 | 0.84 | MAPT (0.58) | MAPTLMNABPTFGALR2GALR1 | |
| SCHEMBL18153389 | 0.81 | ROCK2 (0.56) | MAPTLMNABPTFGALR2POLB | |
| SCHEMBL17673690 | 0.81 | MAPT (0.77) | MAPTLMNAPOLBNPSR1ALDH1A1 | |
| SCHEMBL21815386 | 0.77 | GBA1 (0.51) | MAPTLMNANPSR1ALDH1A1KDM4E | |
| SCHEMBL18153275 | 0.76 | GALR2 (0.48) | MAPTCCNE1CDK2GALR2SMN1; SMN2 | |
| SCHEMBL18153277 | 0.75 | BPTF (0.55) | MAPTLMNABPTFALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3283472-A1 | HEPATITIS B VIRAL ASSEMBLY EFFECTORS | Indiana University Research&Technology Corporation (US) | 2018-02-21 | — | — | EP | disclosed |
| WO-2016168619-A1 | HEPATITIS B VIRAL ASSEMBLY EFFECTORS | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2016-10-20 | — | — | WO | disclosed |