Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 2/20 | 0.75 |
| ▸ | RAB9A | P51151 | 6/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.74 |
| ▸ | MEN1 | O00255 | 5/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.74 |
| ▸ | NPC1 | O15118 | 5/20 | 0.74 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.74 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.74 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.74 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.74 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.74 |
| ▸ | RELA | Q04206 | 3/20 | 0.74 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.74 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.73 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.73 |
| ▸ | MAPT | P10636 | 6/20 | 0.73 |
| ▸ | HPGD | P15428 | 5/20 | 0.73 |
| ▸ | TP53 | P04637 | 5/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Irisolidone SCHEMBL1974327 | 0.90 | EGFR (0.84) | ABCB1RAB9ASMN1; SMN2MEN1KMT2A | |
| Irisolidone SCHEMBL30997344 | 0.90 | EGFR (0.84) | ABCB1RAB9ASMN1; SMN2MEN1KMT2A | |
| 4',7-Dimethoxy-5-Hydroxygenistein SCHEMBL572108 | 0.85 | RAB9A (1.00) | ABCB1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL30525493 | 0.85 | MAPT (0.75) | ABCB1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL13279932 | 0.85 | MAPT (0.75) | ABCB1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL28740045 | 0.85 | PTPN1 (0.70) | ABCB1RAB9ASMN1; SMN2MEN1KMT2A | |
| Biochanin SCHEMBL61258 | 0.84 | RAB9A (1.00) | ABCB1RAB9ASMN1; SMN2MEN1KMT2A | |
| Biochanin SCHEMBL29410271 | 0.84 | RAB9A (1.00) | ABCB1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL28469105 | 0.84 | ALDH1A1 (0.67) | ABCB1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL12892701 | 0.83 | RAB9A (0.81) | ABCB1RAB9ASMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118994280-A | Isoflavone glycoside compound with osteoporosis resisting effect, and its extraction method and application | 湖北大学 | 2024-11-22 | — | — | CN | disclosed |
| EP-4408415-A1 | ISOFLAVONE DERIVATIVES MODULATING MUTANT BESTROPHIN 1 FOR TREATMENT OF BEST1-RELATED RETINOPATHIES | Universität Regensburg (DE) | 2024-08-07 | — | — | EP | disclosed |
| WO-2023052579-A1 | ISOFLAVONE DERIVATIVES MODULATING MUTANT BESTROPHIN 1 FOR TREATMENT OF BEST1-RELATED RETINOPATHIES | UNIVERSITÄT REGENSBURG (DE) | 2023-04-06 | — | — | WO | disclosed |
| CN-112915096-B | Pharmaceutical application of echinocystic acid-28-O-beta-D-glucoside | 天津中医药大学 | 2022-12-20 | — | — | CN | disclosed |
| CN-112972461-B | Comprises 5-aldehyde-2, 2'; pharmaceutical use of pharmaceutical composition of 5', 2' -trighiol | 天津中医药大学 | 2022-09-20 | — | — | CN | disclosed |