Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 4/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | PRNP | P04156 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29932118 | 0.85 | GAA (0.38) | LMNAGAAHTTTP53SMN1; SMN2 | |
| SCHEMBL29932225 | 0.85 | GAA (0.40) | LMNAGAAHTTTP53SMN1; SMN2 | |
| SCHEMBL29931997 | 0.84 | GAA (0.38) | LMNAGAAHTTTP53SMN1; SMN2 | |
| SCHEMBL29931920 | 0.83 | GAA (0.37) | LMNAGAAHTTTP53SMN1; SMN2 | |
| SCHEMBL29931771 | 0.81 | GAA (0.35) | LMNAGAAHTTTP53SMN1; SMN2 | |
| SCHEMBL29932150 | 0.81 | LMNA (0.38) | LMNAGAAHTTTP53SMN1; SMN2 | |
| SCHEMBL29932108 | 0.79 | ALDH1A1 (0.43) | LMNAGAAHTTTP53SMN1; SMN2 | |
| SCHEMBL30232726 | 0.78 | LMNA (0.41) | LMNAGAAHTTTP53SMN1; SMN2 | |
| SCHEMBL29931836 | 0.73 | GAA (0.34) | LMNAGAAHTTTP53SMN1; SMN2 | |
| SCHEMBL23536473 | 0.73 | LMNA (0.30) | LMNAGAAHTTTP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115087440-A | TRPML modulators | 卡斯玛治疗公司 | 2022-09-20 | — | — | CN | disclosed |