Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | APAF1 | O14727 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.41 |
| ▸ | FDPS | P14324 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3399070 | 0.98 | SMN1; SMN2 (0.42) | MEN1APAF1NPC1PLA2G1BHSP90AA1 | |
| SCHEMBL25362418 | 0.94 | MEN1 (0.40) | MEN1APAF1NPC1PLA2G1BHSP90AA1 | |
| SCHEMBL13255991 | 0.92 | SMN1; SMN2 (0.45) | MEN1APAF1NPC1PLA2G1BHSP90AA1 | |
| SCHEMBL1219035 | 0.89 | MEN1 (0.47) | MEN1APAF1NPC1PLA2G1BHSP90AA1 | |
| SCHEMBL1219462 | 0.89 | MEN1 (0.47) | MEN1APAF1NPC1PLA2G1BHSP90AA1 | |
| SCHEMBL15324343 | 0.89 | MEN1 (0.47) | MEN1APAF1NPC1PLA2G1BHSP90AA1 | |
| SCHEMBL1219710 | 0.89 | MEN1 (0.47) | MEN1APAF1NPC1PLA2G1BHSP90AA1 | |
| SCHEMBL15323525 | 0.87 | MEN1 (0.53) | MEN1APAF1NPC1PLA2G1BHSP90AA1 | |
| SCHEMBL1217990 | 0.87 | MEN1 (0.53) | MEN1APAF1NPC1PLA2G1BHSP90AA1 | |
| SCHEMBL1219357 | 0.85 | MEN1 (0.54) | MEN1APAF1NPC1PLA2G1BHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11152642-B2 | Hybrid electrolyte, and electrode and lithium battery each including the same | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2021-10-19 | — | — | US | disclosed |
| US-20200136177-A1 | HYBRID ELECTROLYTE, AND ELECTRODE AND LITHIUM BATTERY EACH INCLUDING THE SAME | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2020-04-30 | — | — | US | disclosed |
| EP-1954680-B1 | IONIC LIQUIDS | DU PONT (US) | 2012-05-23 | — | — | EP | disclosed |
| US-7838679-B2 | Pyridinium cation and fluoroalkylsulfonate or fluoroalkylsulfonimide anions; solvents and catalysts | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-11-23 | — | — | US | disclosed |
| US-7838684-B2 | Fluorinated anions; cation selected from pyridinium, pyridazinium, pyrimidinium, pyrazinium, imidazolium, pyrazolium, thiazolium, oxazolium, triazolium, and phosphonium, ammonium cations with specified substituents, and anion is fluorinated sulfonium, sulfonylimide | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-11-23 | — | — | US | disclosed |
| US-7834189-B2 | Oxazolium cation and fluoroalkylsulfonate or fluoroalkylsulfonimide anions; solvents and catalysts | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-11-16 | — | — | US | disclosed |
| US-7834192-B2 | Ionic liquids | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-11-16 | — | — | US | disclosed |
| US-7829722-B2 | Ionic liquids | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-11-09 | — | — | US | disclosed |
| US-7829739-B2 | Ionic liquids | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-11-09 | — | — | US | disclosed |
| US-7829706-B2 | Ionic liquids | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-11-09 | — | — | US | disclosed |
| US-7238772-B2 | Preparation of polytrimethylene ether glycol and copolymers thereof | E. I. DU PONT DE NEMOURS AND COMPANY (DE) | 2007-07-03 | — | — | US | disclosed |
| US-20070100181-A1 | Olefin isomerization | E. I. DU PONT DE NEMOURS AND COMPANY | 2007-05-03 | — | — | US | disclosed |
| US-20070100184-A1 | Alkylation of aromatic compounds | E. I. DU PONT DE NEMOURS AND COMPANY | 2007-05-03 | — | — | US | disclosed |
| WO-2007050491-A2 | OLEFIN ISOMERIZATION | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-05-03 | — | — | WO | disclosed |
| WO-2007050492-A1 | ALKYLATION OF AROMATIC COMPOUNDS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-05-03 | — | — | WO | disclosed |
| WO-2007038360-A2 | PREPARATION OF POLYTRIMETHYLENE ETHER GLYCOL AND COPOLYMERS THEREOF | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-04-05 | — | — | WO | disclosed |
| WO-2007038359-A1 | IONIC LIQUIDS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-04-05 | — | — | WO | disclosed |
| US-20070066854-A1 | Preparation of polytrimethylene ether glycol and copolymers thereof | THE CHEMOURS COMPANY FC, LLC | 2007-03-22 | — | — | US | disclosed |
| US-20070066852-A1 | Preparation of poly(tetramethylene) glycol | THE CHEMOURS COMPANY FC, LLC | 2007-03-22 | — | — | US | disclosed |
| US-20070066822-A1 | Ionic liquids | THE CHEMOURS COMPANY FC, LLC | 2007-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070100184-A1 | Alkylation of aromatic compounds | TYR, ALK, AHR | MEN1 1923/4885APAF1 329/4885NPC1 2753/4885 |
| US-20070066854-A1 | Preparation of polytrimethylene ether glycol and copolymers thereof | PARG, PTGES3, PGD | MEN1 1773/4885APAF1 1602/4885NPC1 4723/4885 |
| US-20070100181-A1 | Olefin isomerization | OSBP, OXER1, ALOX12 | MEN1 3487/4885APAF1 1394/4885NPC1 518/4885 |
| US-20070066822-A1 | Ionic liquids | AFF2, AFF1, ZYX | MEN1 1207/4885APAF1 3882/4885NPC1 4270/4885 |
| US-20070066852-A1 | Preparation of poly(tetramethylene) glycol | PARG, PUF60, TPR | MEN1 322/4885APAF1 2585/4885NPC1 2084/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.