Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CCKBR | P32239 | 1/20 | 0.38 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.37 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.37 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29933737 | 0.98 | DRD2 (0.41) | DRD2DRD3ALOX5KDM4EALDH1A1 | |
| SCHEMBL11038954 | 0.95 | DRD2 (0.43) | DRD2DRD3ALOX5KDM4EALDH1A1 | |
| SCHEMBL28088464 | 0.84 | KDM4E (0.45) | DRD2DRD3ALOX5KDM4EALDH1A1 | |
| SCHEMBL28890610 | 0.84 | KDM4E (0.45) | DRD2DRD3ALOX5KDM4EALDH1A1 | |
| SCHEMBL10774538 | 0.84 | KDM4E (0.45) | DRD2DRD3ALOX5KDM4EALDH1A1 | |
| SCHEMBL11168360 | 0.83 | ALOX5 (0.43) | DRD2DRD3ALOX5KDM4EALDH1A1 | |
| SCHEMBL30335497 | 0.83 | ALOX5 (0.43) | DRD2DRD3ALOX5KDM4EALDH1A1 | |
| SCHEMBL9225107 | 0.82 | DRD2 (0.44) | DRD2DRD3ALOX5KDM4EALDH1A1 | |
| SCHEMBL30863902 | 0.82 | DRD2 (0.45) | DRD2DRD3ALOX5KDM4EALDH1A1 | |
| SCHEMBL9227391 | 0.81 | KDM4E (0.42) | DRD2DRD3ALOX5KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109879790-B | Amide micromolecule organic compound with indole or indole analogue as mother nucleus structure, application and preparation method thereof | 华东师范大学 | 2022-09-20 | — | — | CN | disclosed |