Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 7/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.46 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.44 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.43 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | SGMS2 | Q8NHU3 | 2/20 | 0.42 |
| ▸ | SYK | P43405 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31359341 | 0.80 | MKNK1 (0.46) | PARP1LMNAKMT2AMKNK1MKNK2 | |
| SCHEMBL8034556 | 0.79 | PARP1 (0.61) | PARP1HTTLMNAAKR1C1MEN1 | |
| SCHEMBL29934036 | 0.75 | IRAK4 (0.49) | PARP1HTTMKNK1MKNK2 | |
| SCHEMBL28884716 | 0.74 | RXRA (0.48) | KMT2A | |
| SCHEMBL29934080 | 0.74 | RXRA (0.48) | KMT2A | |
| SCHEMBL718082 | 0.74 | PARP1 (0.79) | PARP1HTTLMNAAKR1C1MEN1 | |
| SCHEMBL28884605 | 0.72 | MAPT (0.46) | HTTLMNAKMT2ARAB9A | |
| SCHEMBL3757098 | 0.72 | PARP10 (0.60) | PARP1HTTLMNAAKR1C1MEN1 | |
| SCHEMBL15452748 | 0.71 | PARP1 (0.65) | PARP1HTTLMNAAKR1C1PARP2 | |
| SCHEMBL12505427 | 0.71 | PARP1 (0.64) | PARP1HTTLMNAAKR1C1PARP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115315421-A | Compounds and compositions as PDGF receptor kinase inhibitors | 日本新药株式会社 | 2022-11-08 | — | — | CN | disclosed |