Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 4/20 | 0.46 |
| ▸ | MKNK2 | Q9HBH9 | 4/20 | 0.46 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | RXRG | P48443 | 1/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 4/20 | 0.39 |
| ▸ | SIRT3 | Q9NTG7 | 4/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | PPIA | P62937 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29934080 | 0.90 | RXRA (0.48) | ALDH1A1KMT2ARXRARXRBRXRG | |
| SCHEMBL28884716 | 0.90 | RXRA (0.48) | ALDH1A1KMT2ARXRARXRBRXRG | |
| SCHEMBL28884605 | 0.88 | MAPT (0.46) | SMPD1ALDH1A1KMT2ARXRARXRB | |
| SCHEMBL29933855 | 0.80 | PARP1 (0.56) | MKNK1MKNK2KMT2APARP1LMNA | |
| SCHEMBL28884599 | 0.79 | SMPD1 (0.50) | MKNK1MKNK2SMPD1ALDH1A1KMT2A | |
| SCHEMBL29934013 | 0.79 | SMPD1 (0.50) | MKNK1MKNK2SMPD1ALDH1A1KMT2A | |
| SCHEMBL31359352 | 0.79 | DDR2 (0.53) | MKNK1MKNK2 | |
| SCHEMBL29932967 | 0.78 | CNR1 (0.49) | — | |
| SCHEMBL71773 | 0.78 | PARP10 (0.59) | SMPD1RXRARXRBRXRGPARP10 | |
| SCHEMBL23501599 | 0.77 | CYP11B1 (0.54) | MKNK1MKNK2SMPD1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119371371-A | Compounds and compositions as PDGF receptor kinase inhibitors | 日本新药株式会社 | 2025-01-28 | — | — | CN | disclosed |
| CN-115315421-B | Compounds and compositions as PDGF receptor kinase inhibitors | 日本新药株式会社 | 2024-12-03 | — | — | CN | disclosed |