Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR2 | O15552 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.39 |
| ▸ | RAB9A | P51151 | 6/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 5/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.36 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.36 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.36 |
| ▸ | GSK3B | P49841 | 2/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29933906 | 0.94 | FFAR2 (0.43) | FFAR2SMN1; SMN2RAB9AMAPK14KDM4E | |
| SCHEMBL3129613 | 0.76 | RAB9A (0.58) | FFAR2SMN1; SMN2RAB9AMAPK14KDM4E | |
| SCHEMBL19710761 | 0.76 | MAPK14 (0.57) | FFAR2SMN1; SMN2RAB9AMAPK14KDM4E | |
| SCHEMBL4557739 | 0.72 | MAPK14 (0.50) | FFAR2SMN1; SMN2RAB9AMAPK14KDM4E | |
| SCHEMBL14887666 | 0.70 | FFAR2 (0.46) | FFAR2SMN1; SMN2RAB9AMAPK14KDM4E | |
| SCHEMBL4729955 | 0.68 | MAPK13 (0.48) | FFAR2SMN1; SMN2RAB9AMAPK14KDM4E | |
| SCHEMBL27848064 | 0.68 | FYN (0.46) | FFAR2MAPK14GSK3BDYRK1ADYRK1B | |
| SCHEMBL28790897 | 0.67 | MAPK14 (0.44) | FFAR2SMN1; SMN2RAB9AMAPK14NPC1 | |
| SCHEMBL27829685 | 0.67 | MAPK14 (0.44) | FFAR2SMN1; SMN2RAB9AMAPK14NPC1 | |
| SCHEMBL29606406 | 0.67 | MAPK14 (0.54) | FFAR2SMN1; SMN2RAB9AMAPK14ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115315421-A | Compounds and compositions as PDGF receptor kinase inhibitors | 日本新药株式会社 | 2022-11-08 | — | — | CN | disclosed |