Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 5/20 | 0.44 |
| ▸ | SRC | P12931 | 5/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.40 |
| ▸ | ALPL | P05186 | 2/20 | 0.39 |
| ▸ | BCR | P11274 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | NEK1 | Q96PY6 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28884710 | 0.89 | KDM4C (0.43) | ABL1SRCCYP11B2ALPLKDM4C | |
| SCHEMBL29934030 | 0.89 | KDM4C (0.43) | ABL1SRCCYP11B2ALPLKDM4C | |
| SCHEMBL31359374 | 0.88 | MKNK1 (0.38) | ABL1SRCCYP11B2ALPLKDM4C | |
| SCHEMBL23501668 | 0.82 | PKM (0.44) | ABL1SRCHIF1AALOX5HTT | |
| SCHEMBL29933965 | 0.82 | PKM (0.44) | ABL1SRCHIF1AALOX5HTT | |
| SCHEMBL29934041 | 0.82 | KCNH2 (0.43) | ABL1SRCCYP11B2KDM4CRAB9A | |
| SCHEMBL28884674 | 0.78 | DDR1 (0.47) | SLC2A1CYP19A1CYP11B1CYP11B2ALOX15 | |
| SCHEMBL29932961 | 0.78 | CNR1 (0.42) | — | |
| SCHEMBL29932952 | 0.78 | CNR1 (0.42) | — | |
| SCHEMBL31359380 | 0.76 | MKNK1 (0.53) | CYP11B2KDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115315421-A | Compounds and compositions as PDGF receptor kinase inhibitors | 日本新药株式会社 | 2022-11-08 | — | — | CN | disclosed |