Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 7/20 | 0.38 |
| ▸ | MKNK2 | Q9HBH9 | 7/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.36 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | VNN1 | O95497 | 1/20 | 0.36 |
| ▸ | ALPL | P05186 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28884710 | 0.90 | KDM4C (0.43) | KDM4CKCNH2CYP11B2ABL1SRC | |
| SCHEMBL29934030 | 0.90 | KDM4C (0.43) | KDM4CKCNH2CYP11B2ABL1SRC | |
| SCHEMBL28884685 | 0.88 | ABL1 (0.44) | KDM4CCYP11B2ABL1SRCALPL | |
| SCHEMBL31359380 | 0.88 | MKNK1 (0.53) | MKNK1MKNK2KDM4CCYP11B2 | |
| SCHEMBL29934041 | 0.87 | KCNH2 (0.43) | KDM4CKCNH2CYP11B2ABL1SRC | |
| SCHEMBL29932952 | 0.79 | CNR1 (0.42) | — | |
| SCHEMBL29932961 | 0.79 | CNR1 (0.42) | — | |
| SCHEMBL31359352 | 0.78 | DDR2 (0.53) | MKNK1MKNK2PTK2DDR1DDR2 | |
| SCHEMBL29934245 | 0.78 | HDAC1 (0.43) | KCNH2CYP11B2DDR1DDR2ABL1 | |
| SCHEMBL29934825 | 0.76 | CYP11B2 (0.33) | KCNH2PTK2CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119371371-A | Compounds and compositions as PDGF receptor kinase inhibitors | 日本新药株式会社 | 2025-01-28 | — | — | CN | disclosed |
| CN-115315421-B | Compounds and compositions as PDGF receptor kinase inhibitors | 日本新药株式会社 | 2024-12-03 | — | — | CN | disclosed |