SCHEMBL29934196

SCHEMBL29934196

NCc1cc2ccccc2oc1=O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.59
SMN1; SMN2 Q16637 1/20 0.59
MAOA P21397 2/20 0.58
MAOB P27338 6/20 0.56
LOXL2 Q9Y4K0 1/20 0.56
MMP2 P08253 1/20 0.55
MMP9 P14780 1/20 0.55
ADAM17 P78536 1/20 0.55
TYR P14679 1/20 0.55
DAO P14920 1/20 0.55
AKR1B1 P15121 1/20 0.55
HPGD P15428 1/20 0.55
CA12 O43570 3/20 0.53
CA9 Q16790 3/20 0.53
CA1 P00915 2/20 0.53
CA2 P00918 1/20 0.53
RAB9A P51151 3/20 0.51
KDM4E B2RXH2 2/20 0.51
ALDH1A1 P00352 1/20 0.51
CA3 P07451 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL94133 1.00 POLB (0.59) POLBSMN1; SMN2MAOAMAOBLOXL2
SCHEMBL3237487 0.98 POLB (0.58) POLBSMN1; SMN2MAOAMAOBLOXL2
Butane SCHEMBL20446706 0.93 MAOB (0.62) POLBSMN1; SMN2MAOAMAOBLOXL2
Carbamic Acid SCHEMBL8995121 0.92 MMP2 (0.56) POLBSMN1; SMN2MAOAMAOBLOXL2
Coumarin SCHEMBL17312324 0.91 CA12 (0.61) POLBSMN1; SMN2MAOAMAOBLOXL2
Acetic Acid SCHEMBL472753 0.91 MAOB (0.56) POLBSMN1; SMN2MAOAMAOBMMP2
SCHEMBL30311162 0.86 MMP2 (0.60) POLBSMN1; SMN2MAOAMAOBLOXL2
SCHEMBL5678818 0.85 MAOA (0.52) POLBSMN1; SMN2MAOAMAOBLOXL2
SCHEMBL13612673 0.85 MAOA (0.61) POLBSMN1; SMN2MAOAMAOBMMP2
SCHEMBL27625488 0.85 MMP2 (0.67) POLBSMN1; SMN2MAOAMAOBMMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3891752-B1 METHOD FOR DETECTING THE PRESENCE, IDENTIFICATION AND QUANTIFICATION IN A BLOOD SAMPLE OF ANTICOAGULANTS WHICH ARE INHIBITORS OF BLOOD COAGULATION ENZYMES, AND MEANS FOR THE IMPLEMENTATION THEREOF STAGO DIAGNOSTICA (FR) 2025-08-13 EP disclosed
EP-4172600-A1 SYSTEMS AND METHODS FOR SIMULTANEOUS NEAR-INFRARED LIGHT AND VISIBLE LIGHT IMAGING Blaze Bioscience, Inc. (US) 2023-05-03 EP disclosed
EP-4090761-A2 A DNA-BASED VOLTMETER FOR ORGANELLES The University of Chicago (US) 2022-11-23 EP disclosed
EP-4076500-A1 METHODS OF TREATING VASCULAR LESIONS AND MALFORMATIONS Blaze Bioscience, Inc. (US) 2022-10-26 EP disclosed
EP-4058810-A1 DEVICE AND METHOD FOR ANALYTE DETECTION President And Fellows Of Harvard College (US) 2022-09-21 EP disclosed