SCHEMBL29934272

SCHEMBL29934272

CC(C)C[C@H](NC(=O)[C@H](CS)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](N)CS)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCCNC(=N)N)C(=O)O

nearest known ligand 0.57

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ NMUR2 Q9GZQ4 6/20 0.57
▸ NMUR1 Q9HB89 6/20 0.57
▸ NPY4R P50391 6/20 0.53
▸ NPY1R P25929 5/20 0.53
▸ NPY2R P49146 2/20 0.53
▸ NPY5R Q15761 2/20 0.53
▸ RAMP3 O60896 1/20 0.52
▸ CALCR P30988 1/20 0.52
▸ NTSR2 O95665 1/20 0.51
▸ NTSR1 P30989 1/20 0.51
▸ CXCR4 P61073 2/20 0.50
▸ MAPK8 P45983 1/20 0.50
▸ MAPK9 P45984 1/20 0.50
▸ MAPK10 P53779 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29934595 0.91 NMUR2 (0.58) NMUR2NMUR1RAMP3CALCRNTSR1
SCHEMBL31187483 0.86 NMUR2 (0.63) NMUR2NMUR1NPY4RNPY1RNPY2R
SCHEMBL30895016 0.86 RAMP3 (0.64) NMUR2NMUR1NPY4RNPY1RNPY2R
SCHEMBL30792437 0.86 NMUR2 (0.56) NMUR2NMUR1NPY4RNPY1RNPY2R
SCHEMBL30678863 0.86 NMUR2 (0.56) NMUR2NMUR1
SCHEMBL31473044 0.85 NMUR2 (0.58) NMUR2NMUR1MAPK8MAPK9MAPK10
SCHEMBL30695569 0.85 OPRM1 (0.56) NMUR2NMUR1NTSR2NTSR1
SCHEMBL32681766 0.85 APLNR (0.59) NPY4RNPY1RNPY2RNPY5RCALCR
SCHEMBL16566024 0.85 RAMP3 (0.62) NPY4RNPY1RNPY2RNPY5RRAMP3
SCHEMBL31679344 0.84 NTSR1 (0.60) NMUR2NMUR1NPY1RNTSR2NTSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026102332-A1 NERVE AND TUMOR HOMING AGENTS AND METHODS OF USE THEREOF Blaze Bioscience, Inc. (US) 2026-05-15 — — WO disclosed
US-12048732-B2 Methods of treating breast cancer Blaze Bioscience, Inc. (US) 2024-07-30 — — US disclosed
US-20230257428-A1 METHODS OF TREATMENT USING CHLOROTOXIN CONJUGATES Blaze Bioscience, Inc. 2023-08-17 — — US disclosed
US-20230037660-A1 METHODS OF TREATING VASCULAR LESIONS AND MALFORMATIONS Blaze Bioscience, Inc. 2023-02-09 — — US disclosed
EP-4076500-A1 METHODS OF TREATING VASCULAR LESIONS AND MALFORMATIONS Blaze Bioscience, Inc. (US) 2022-10-26 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230257428-A1 METHODS OF TREATMENT USING CHLOROTOXIN CONJUGATES CHLSN, SLC47A1, CLSPN NMUR2 1904/4885NMUR1 1551/4885NPY4R 2341/4885
US-20230037660-A1 METHODS OF TREATING VASCULAR LESIONS AND MALFORMATIONS FLT4, FLT1, KDR NMUR2 903/4885NMUR1 705/4885NPY4R 938/4885
US-12048732-B2 Methods of treating breast cancer BRCA1, HUNK, MLEC NMUR2 1088/4885NMUR1 719/4885NPY4R 522/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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