Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | CSF1R | P07333 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | KIT | P10721 | 5/20 | 0.40 |
| ▸ | DDR1 | Q08345 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | BCR | P11274 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23501801 | 1.00 | POLB (0.46) | POLBHCAR2HTTCSF1RRAB9A | |
| SCHEMBL29934016 | 0.84 | HCAR2 (0.46) | POLBHCAR2HTTRAB9AGRM5 | |
| SCHEMBL28884697 | 0.84 | HCAR2 (0.46) | POLBHCAR2HTTRAB9AGRM5 | |
| SCHEMBL4062149 | 0.83 | CSF1R (0.46) | HCAR2CSF1RGRM5KITDDR1 | |
| SCHEMBL4063968 | 0.80 | CSF1R (0.62) | HCAR2CSF1RGRM5KITDDR1 | |
| SCHEMBL29933030 | 0.79 | TAS1R3 (0.48) | CSF1RKITDDR1ABL1BCR | |
| SCHEMBL14616920 | 0.77 | HAO1 (0.50) | CSF1RRAB9AKITDDR1TSHR | |
| SCHEMBL22529514 | 0.76 | LCK (0.57) | CSF1RKITDDR1ABL1BCR | |
| SCHEMBL29934174 | 0.75 | CSF1R (0.43) | HCAR2CSF1RGRM5KITDDR1 | |
| SCHEMBL11298523 | 0.73 | ABL1 (0.64) | RAB9AKITDDR1ABL1BCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119371371-A | Compounds and compositions as PDGF receptor kinase inhibitors | 日本新药株式会社 | 2025-01-28 | — | — | CN | disclosed |
| CN-115315421-B | Compounds and compositions as PDGF receptor kinase inhibitors | 日本新药株式会社 | 2024-12-03 | — | — | CN | disclosed |
| CN-115315421-A | Compounds and compositions as PDGF receptor kinase inhibitors | 日本新药株式会社 | 2022-11-08 | — | — | CN | disclosed |