Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.36 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28884697 | 1.00 | HCAR2 (0.46) | HCAR2POLBTSHRHTTALOX15 | |
| SCHEMBL23501639 | 0.85 | ALDH1A1 (0.41) | TSHRHTTRAB9AGRM5MAPT | |
| SCHEMBL29934096 | 0.85 | ALDH1A1 (0.41) | TSHRHTTRAB9AGRM5MAPT | |
| SCHEMBL29934281 | 0.84 | POLB (0.46) | HCAR2POLBTSHRHTTALOX15 | |
| SCHEMBL23501801 | 0.84 | POLB (0.46) | HCAR2POLBTSHRHTTALOX15 | |
| SCHEMBL29933160 | 0.79 | TAS1R3 (0.46) | MEN1KMT2A | |
| SCHEMBL1921254 | 0.77 | TSHR (0.52) | TSHRRAB9AMAPTALDH1A1HAO1 | |
| SCHEMBL21201466 | 0.70 | ADH5 (0.52) | HCAR2POLBTSHRHTTALOX15 | |
| SCHEMBL27974410 | 0.69 | KIT (0.60) | — | |
| SCHEMBL1477046 | 0.68 | GRM5 (0.55) | HTTALOX15GRM5MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119371371-A | Compounds and compositions as PDGF receptor kinase inhibitors | 日本新药株式会社 | 2025-01-28 | — | — | CN | disclosed |
| CN-115315421-B | Compounds and compositions as PDGF receptor kinase inhibitors | 日本新药株式会社 | 2024-12-03 | — | — | CN | disclosed |
| CN-115315421-A | Compounds and compositions as PDGF receptor kinase inhibitors | 日本新药株式会社 | 2022-11-08 | — | — | CN | disclosed |