SCHEMBL29934320

SCHEMBL29934320

Cc1cc(O)cc(Oc2cc(O)c(O)c(C(=O)O)c2)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 1/20 0.45
MCL1 Q07820 3/20 0.44
BCL2L1 Q07817 2/20 0.44
HCAR1 Q9BXC0 1/20 0.44
GLO1 Q04760 1/20 0.40
XDH P47989 2/20 0.40
SLC22A12 Q96S37 1/20 0.40
CSNK2A1 P68400 1/20 0.40
ALDH1A1 P00352 4/20 0.38
CA12 O43570 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
TSHR P16473 1/20 0.38
CA7 P43166 1/20 0.38
CA9 Q16790 1/20 0.38
CA14 Q9ULX7 1/20 0.38
HMGB1 P09429 1/20 0.37
CXCL12 P48061 1/20 0.37
SELL P14151 1/20 0.36
SELP P16109 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Diorcinol SCHEMBL28744720 0.78 ALDH1A1 (0.60) PTPN1HCAR1ALDH1A1CA2TSHR
Diorcinol SCHEMBL29629136 0.78 ALDH1A1 (0.60) PTPN1HCAR1ALDH1A1CA2TSHR
SCHEMBL28367094 0.78 HCAR1 (0.54) PTPN1HCAR1GLO1ALDH1A1CA12
SCHEMBL29807406 0.78 HCAR1 (0.54) PTPN1HCAR1GLO1ALDH1A1CA12
SCHEMBL29807828 0.78 HCAR1 (0.69) PTPN1HCAR1ALDH1A1CA12CA1
SCHEMBL28363894 0.78 HCAR1 (0.69) PTPN1HCAR1ALDH1A1CA12CA1
SCHEMBL16431698 0.77 CYP3A4 (0.61) PTPN1MCL1BCL2L1HCAR1GLO1
SCHEMBL31335826 0.77 CSNK2A1 (0.57) MCL1HCAR1CSNK2A1ALDH1A1CA12
SCHEMBL5940950 0.77 CSNK2A1 (0.57) MCL1HCAR1CSNK2A1ALDH1A1CA12
SCHEMBL18341497 0.75 NPC1 (0.53) MCL1ALDH1A1CA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115322169-A Polyketone compounds, preparation method and application thereof 自然资源部第三海洋研究所 2022-11-11 CN disclosed