Diorcinol

Diorcinol

SCHEMBL29629136

Cc1cc(O)cc(Oc2cc(C)cc(O)c2)c1

nearest known ligand 0.60

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.60
PTPN1 P18031 1/20 0.58
SMN1; SMN2 Q16637 2/20 0.48
HSP90AA1 P07900 1/20 0.43
HCAR1 Q9BXC0 1/20 0.43
POLB P06746 3/20 0.42
CYP3A4 P08684 2/20 0.41
TSHR P16473 1/20 0.41
MAPK1 P28482 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
BACE1 P56817 1/20 0.39
ACHE P22303 2/20 0.39
KMT2A Q03164 2/20 0.38
SELL P14151 1/20 0.38
SELP P16109 1/20 0.38
SELE P16581 1/20 0.38
MEN1 O00255 1/20 0.38
ESR1 P03372 1/20 0.38
ESR2 Q92731 1/20 0.38
CA2 P00918 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Diorcinol SCHEMBL28744720 1.00 ALDH1A1 (0.60) ALDH1A1PTPN1SMN1; SMN2HSP90AA1HCAR1
SCHEMBL29215231 0.87 LTA4H (0.54) ALDH1A1PTPN1SMN1; SMN2CYP3A4TSHR
SCHEMBL30358251 0.85 ACHE (0.54) ALDH1A1PTPN1SMN1; SMN2HSP90AA1CYP3A4
SCHEMBL29807828 0.82 HCAR1 (0.69) ALDH1A1PTPN1HCAR1POLBKMT2A
SCHEMBL28363894 0.82 HCAR1 (0.69) ALDH1A1PTPN1HCAR1POLBKMT2A
SCHEMBL296714 0.82 PTPN1 (0.67) ALDH1A1PTPN1SMN1; SMN2POLBCYP3A4
SCHEMBL31507600 0.82 PTPN1 (0.67) ALDH1A1PTPN1SMN1; SMN2POLBCYP3A4
Cordyol C SCHEMBL29979417 0.81 POLB (0.60) ALDH1A1PTPN1SMN1; SMN2HCAR1POLB
SCHEMBL18415180 0.80 ALDH1A1 (0.55) ALDH1A1PTPN1SMN1; SMN2HCAR1POLB
SCHEMBL31376380 0.80 PTPN1 (0.65) ALDH1A1PTPN1SMN1; SMN2POLBCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114426984-B Plasmid for regulating and controlling secondary metabolite of filamentous fungi and application thereof 浙江大学 2024-06-07 CN disclosed
CN-117945867-A Antibacterial active benzyl phenyl ether derivative and preparation method thereof 海南师范大学 2024-04-30 CN disclosed
CN-115322169-B Polyketone compound and preparation method and application thereof 自然资源部第三海洋研究所 2024-02-06 CN disclosed
CN-114426984-A Plasmid for regulating and controlling secondary metabolite of filamentous fungus and application thereof 浙江大学 2022-05-03 CN disclosed