Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.32 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.30 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6677120 | 1.00 | MAOA (0.37) | MAOAMAOBKCNE1KCNQ1MEN1 | |
| SCHEMBL28700213 | 0.89 | MAOA (0.34) | MAOAMAOBKCNE1KCNQ1MEN1 | |
| SCHEMBL5044777 | 0.83 | MAOA (0.37) | MAOAMAOBKCNE1KCNQ1MEN1 | |
| SCHEMBL27969569 | 0.80 | CYP2C19 (0.35) | MAOAMAOBKCNE1KCNQ1MEN1 | |
| SCHEMBL28148368 | 0.80 | — | — | |
| SCHEMBL22716169 | 0.78 | MEN1 (0.35) | MAOAMAOBMEN1KMT2ANPC1 | |
| SCHEMBL5170577 | 0.76 | GUSB (0.38) | MAOAMAOBMEN1KMT2AALOX15 | |
| SCHEMBL28653831 | 0.73 | KCNE1 (0.36) | MAOAMAOBKCNE1KCNQ1MEN1 | |
| SCHEMBL29249349 | 0.73 | CHRNB2 (0.36) | MAOAMAOBKCNE1KCNQ1MEN1 | |
| SCHEMBL2045223 | 0.70 | HSP90AA1 (0.40) | MAOAMAOBKCNE1KCNQ1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220291237-A1 | Gene Expression Inflammatory Age and Its Uses | Edifice Health, Inc. (US) | 2022-09-15 | — | — | US | disclosed |