Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 2/20 | 0.47 |
| ▸ | ACACA | Q13085 | 2/20 | 0.47 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 6/20 | 0.40 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.40 |
| ▸ | CETP | P11597 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.36 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.36 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.36 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.36 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.36 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.36 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29934458 | 0.90 | HSD11B1 (0.49) | ACLYACACAPTPN11PTPN1PTGS2 | |
| SCHEMBL30827593 | 0.81 | HSD11B1 (0.42) | ACLYACACAPTPN11PTPN1PTGS2 | |
| SCHEMBL30812411 | 0.80 | ACLY (0.52) | ACLYACACAPTPN11PTGS2HSD11B1 | |
| SCHEMBL13420433 | 0.78 | HSD11B1 (0.54) | ACLYACACAPTPN11PTPN1PTGS2 | |
| SCHEMBL13420513 | 0.78 | HSD11B1 (0.54) | ACLYACACAPTPN11PTPN1PTGS2 | |
| SCHEMBL14046876 | 0.78 | HSD11B1 (0.54) | ACLYACACAPTPN11PTPN1PTGS2 | |
| SCHEMBL13420642 | 0.78 | HSD11B1 (0.54) | ACLYACACAPTPN11PTPN1PTGS2 | |
| SCHEMBL13420201 | 0.78 | HSD11B1 (0.54) | ACLYACACAPTPN11PTPN1PTGS2 | |
| Cyclolaudenol (24S) SCHEMBL3191608 | 0.77 | ACLY (0.67) | ACLYACACAPTPN11PTGS2HSD11B1 | |
| Cyclolaudenol (24S) SCHEMBL679913 | 0.77 | ACLY (0.67) | ACLYACACAPTPN11PTGS2HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220291237-A1 | Gene Expression Inflammatory Age and Its Uses | Edifice Health, Inc. (US) | 2022-09-15 | — | — | US | disclosed |