Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOD1 | P00441 | 1/20 | 0.52 |
| ▸ | KARS1 | Q15046 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | FDPS | P14324 | 8/20 | 0.36 |
| ▸ | GGPS1 | O95749 | 2/20 | 0.36 |
| ▸ | BCL9 | O00512 | 3/20 | 0.34 |
| ▸ | CTNNB1 | P35222 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | PTGES | O14684 | 2/20 | 0.34 |
| ▸ | PNLIP | P16233 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16006769 | 0.77 | KARS1 (0.43) | SOD1KARS1USP2CYP3A4MAPT | |
| Sugiol SCHEMBL1086916 | 0.75 | SOD1 (0.58) | SOD1KARS1USP2CYP3A4MAPT | |
| Sugiol SCHEMBL28605319 | 0.75 | SOD1 (0.58) | SOD1KARS1USP2CYP3A4MAPT | |
| Hypargenin C SCHEMBL13532268 | 0.75 | SOD1 (0.55) | SOD1KARS1USP2CYP3A4MAPT | |
| Hypargenin C SCHEMBL31083234 | 0.75 | SOD1 (0.55) | SOD1KARS1USP2CYP3A4MAPT | |
| Hypargenin C SCHEMBL18290364 | 0.75 | SOD1 (0.55) | SOD1KARS1USP2CYP3A4MAPT | |
| Sugiol SCHEMBL17407685 | 0.75 | SOD1 (0.58) | SOD1KARS1USP2CYP3A4MAPT | |
| SCHEMBL18290200 | 0.74 | SOD1 (0.76) | SOD1KARS1USP2CYP3A4MAPT | |
| SCHEMBL13532266 | 0.74 | SOD1 (0.52) | SOD1KARS1USP2CYP3A4MAPT | |
| Ferruginol SCHEMBL13423521 | 0.69 | KARS1 (0.73) | KARS1USP2CYP3A4MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220291237-A1 | Gene Expression Inflammatory Age and Its Uses | Edifice Health, Inc. (US) | 2022-09-15 | — | — | US | disclosed |