Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOD1 | P00441 | 1/20 | 0.52 |
| ▸ | KARS1 | Q15046 | 1/20 | 0.43 |
| ▸ | FDPS | P14324 | 7/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | PTGES | O14684 | 1/20 | 0.39 |
| ▸ | PNLIP | P16233 | 1/20 | 0.39 |
| ▸ | GGPS1 | O95749 | 3/20 | 0.37 |
| ▸ | USP2 | O75604 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18290200 | 0.79 | SOD1 (0.76) | SOD1KARS1FDPSMEN1KMT2A | |
| Sugiol SCHEMBL17407685 | 0.77 | SOD1 (0.58) | SOD1KARS1FDPSMEN1KMT2A | |
| Hypargenin C SCHEMBL18290364 | 0.77 | SOD1 (0.55) | SOD1KARS1FDPSMEN1KMT2A | |
| Hypargenin C SCHEMBL31083234 | 0.77 | SOD1 (0.55) | SOD1KARS1FDPSMEN1KMT2A | |
| Sugiol SCHEMBL28605319 | 0.77 | SOD1 (0.58) | SOD1KARS1FDPSMEN1KMT2A | |
| Hypargenin C SCHEMBL13532268 | 0.77 | SOD1 (0.55) | SOD1KARS1FDPSMEN1KMT2A | |
| Sugiol SCHEMBL1086916 | 0.77 | SOD1 (0.58) | SOD1KARS1FDPSMEN1KMT2A | |
| SCHEMBL29934500 | 0.74 | SOD1 (0.52) | SOD1KARS1FDPSMEN1KMT2A | |
| SCHEMBL18290243 | 0.70 | SOD1 (0.45) | SOD1KARS1FDPSMEN1KMT2A | |
| SCHEMBL18290291 | 0.70 | KARS1 (0.47) | SOD1KARS1FDPSMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8519007-B2 | Use certain diterpene compounds in the treatment of androgen receptor-associated diseases | ACADEMIA SINICA (TW) | 2013-08-27 | — | — | US | disclosed |
| US-8519007-B2 | Use certain diterpene compounds in the treatment of androgen receptor-associated diseases | ACADEMIA SINICA (TW) | 2013-08-27 | — | — | US | disclosed |
| US-20100022632-A1 | USE CERTAIN DITERPENE COMPOUNDS IN THE TREATMENT OF ANDROGEN RECEPTOR-ASSOCIATED DISEASES | ACADEMIA SINICA (TW) | 2010-01-28 | — | — | US | disclosed |
| US-20100022632-A1 | USE CERTAIN DITERPENE COMPOUNDS IN THE TREATMENT OF ANDROGEN RECEPTOR-ASSOCIATED DISEASES | ACADEMIA SINICA (TW) | 2010-01-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100022632-A1 | USE CERTAIN DITERPENE COMPOUNDS IN THE TREATMENT OF ANDROGEN RECEPTOR-ASSOCIATED DISEASES | AR, CYP17A1, CYP19A1 | SOD1 4841/4885KARS1 3258/4885FDPS 178/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.