Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 5/20 | 0.51 |
| ▸ | ACLY | P53396 | 2/20 | 0.44 |
| ▸ | ACACA | Q13085 | 2/20 | 0.44 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cycloeucalenone SCHEMBL29510991 | 0.90 | HSD11B1 (0.61) | HSD11B1ACLYACACAPTPN11NR1H3 | |
| SCHEMBL29935051 | 0.85 | HSD11B1 (0.47) | HSD11B1ACLYACACAPTPN11PTGS1 | |
| SCHEMBL5824245 | 0.84 | HSD11B1 (0.69) | HSD11B1ACLYACACAPTPN11PTGS1 | |
| SCHEMBL13642408 | 0.80 | ACLY (0.56) | HSD11B1ACLYACACAPTPN11PTGS1 | |
| SCHEMBL13642525 | 0.80 | ACLY (0.56) | HSD11B1ACLYACACAPTPN11PTGS1 | |
| SCHEMBL13642677 | 0.80 | ACLY (0.56) | HSD11B1ACLYACACAPTPN11PTGS1 | |
| SCHEMBL13642725 | 0.80 | ACLY (0.56) | HSD11B1ACLYACACAPTPN11PTGS1 | |
| SCHEMBL13642558 | 0.80 | ACLY (0.56) | HSD11B1ACLYACACAPTPN11PTGS1 | |
| SCHEMBL13420260 | 0.78 | ACLY (0.69) | HSD11B1ACLYACACAPTPN11PTGS1 | |
| SCHEMBL13420519 | 0.74 | ACLY (0.54) | HSD11B1ACLYACACAPTPN11PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023011591-A1 | PROBIOTIC COMPOSITIONS FOR TREATING AND PREVENTING COLORECTAL CANCER | THE CHINESE UNIVERSITY OF HONG KONG (CN) | 2023-02-09 | — | — | WO | disclosed |
| US-20220291237-A1 | Gene Expression Inflammatory Age and Its Uses | Edifice Health, Inc. (US) | 2022-09-15 | — | — | US | disclosed |