Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 6/20 | 0.47 |
| ▸ | ACLY | P53396 | 2/20 | 0.42 |
| ▸ | ACACA | Q13085 | 2/20 | 0.42 |
| ▸ | EP300 | Q09472 | 2/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.38 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | EBP | Q15125 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cycloeucalenone SCHEMBL29510991 | 0.87 | HSD11B1 (0.61) | HSD11B1ACLYACACAPTPN11 | |
| SCHEMBL29934569 | 0.85 | HSD11B1 (0.51) | HSD11B1ACLYACACAPTPN11HSD11B2 | |
| SCHEMBL29511134 | 0.81 | ACLY (0.45) | HSD11B1ACLYACACAEP300PTPN11 | |
| SCHEMBL12634185 | 0.75 | ACLY (0.67) | HSD11B1ACLYACACAEP300PTPN11 | |
| SCHEMBL29510985 | 0.75 | ACLY (0.67) | HSD11B1ACLYACACAEP300PTPN11 | |
| SCHEMBL31237297 | 0.70 | HSD11B1 (0.82) | HSD11B1ACLYACACAPTPN11PTGS1 | |
| SCHEMBL1874653 | 0.70 | ACLY (0.48) | HSD11B1ACLYACACAEP300PTPN11 | |
| SCHEMBL5824299 | 0.69 | HSD11B1 (0.61) | HSD11B1ACLYACACAHSD11B2 | |
| SCHEMBL5824245 | 0.69 | HSD11B1 (0.69) | HSD11B1ACLYACACAPTPN11HSD11B2 | |
| Cycloartenone SCHEMBL29504219 | 0.69 | HSD11B1 (0.61) | HSD11B1ACLYACACAPTPN11PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220291237-A1 | Gene Expression Inflammatory Age and Its Uses | Edifice Health, Inc. (US) | 2022-09-15 | — | — | US | disclosed |