Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | KDM1A | O60341 | 1/20 | 0.50 |
| ▸ | MMP13 | P45452 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | CKS1B | P61024 | 1/20 | 0.47 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CTSB | P07858 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28868891 | 0.87 | SMN1; SMN2 (0.50) | SMN1; SMN2LMNAPKMNPC1RAB9A | |
| SCHEMBL16920966 | 0.84 | NPC1 (0.50) | SMN1; SMN2NPC1RAB9AKDM1AMAPT | |
| SCHEMBL27595525 | 0.84 | MAPT (0.50) | SMN1; SMN2LMNANPC1RAB9AKDM1A | |
| SCHEMBL21338139 | 0.81 | LMNA (0.53) | SMN1; SMN2LMNAPKMNPC1RAB9A | |
| SCHEMBL5695138 | 0.81 | HSD17B10 (0.65) | SMN1; SMN2LMNAPKMNPC1RAB9A | |
| SCHEMBL29953114 | 0.79 | LMNA (0.55) | SMN1; SMN2LMNAPKMNPC1RAB9A | |
| SCHEMBL28269804 | 0.78 | L3MBTL1 (0.55) | SMN1; SMN2LMNAPKMNPC1RAB9A | |
| Bicarbonate SCHEMBL11298239 | 0.77 | KDM4E (0.60) | SMN1; SMN2LMNAPKMNPC1RAB9A | |
| SCHEMBL16743643 | 0.77 | HTT (0.54) | SMN1; SMN2LMNANPC1RAB9AKDM1A | |
| SCHEMBL28269768 | 0.75 | MAPT (0.72) | SMN1; SMN2LMNAPKMRAB9AKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220291237-A1 | Gene Expression Inflammatory Age and Its Uses | Edifice Health, Inc. (US) | 2022-09-15 | — | — | US | disclosed |